Publications by authors named "You-Zhen Wei"

Article Synopsis
  • A clinical study investigated the effectiveness of Lewuyou, a polysaccharide-rich drink from brown seaweeds (fucoidan), in treating H. pylori (Hp) infection, which is commonly managed with antibiotics.
  • Conducted with 85 eligible patients over 4 to 8 weeks, results showed promising Hp eradication rates of 77.6% after 4 weeks and 80.5% after 8 weeks, without any reported adverse events.
  • The study concluded that the drink was both safe and effective in significantly reducing Hp levels in the gastric mucosa among participants.
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Background: Persistent vegetative state (PVS) is a devastating and long-lasting clinical condition with high morbidity and mortality; currently, there are no available effective interventions.

Case Summary: We report the case of an 11-year-old boy with PVS caused by severe intracerebral bleeding in the left hemisphere following anticoagulation treatment. The patient's PVS severity showed no notable improvement after 2-mo neuroprotective treatment and rehabilitation, including nerve growth factor and baclofen, hyperbaric oxygen, and comprehensive bedside rehabilitation therapies.

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Highly effective targeted tumor recognition via vectors is crucial for cancer detection. In contrast to antibodies and proteins, peptides are direct targeting ligands with a low molecular weight. In the present study, a peptide magnetic nanovector platform containing a lipid bilayer was designed using a peptide amphiphile (PA) as a skeleton material in a controlled manner without surface modification.

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Aim: To investigate the preventive effects of the cerebro cellular growth peptide (CCGP) on gentamycin-induced inner ear damage in guinea pigs, and to clarify its mechanism.

Methods: The hypoacusis severity and enzymatic activity in the cochlear hair cells were examined by brainstem auditory evoked potential (BAEP) and histochemistry, respectively. The damaged hair cells was counted in three groups.

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