Non-contact oxygen saturation monitoring for wound healing process using dual-wavelength simultaneous acquisition imaging system.

Here we report the fabrication of a noncontact pulse oximeter system based on a dual-wavelength imaging system and its oxygen saturation monitoring performance during wound healing. The dual-wavelength imaging system consists of 660 nm and 940 nm light-emitting diodes and a multi-spectral camera that simultaneously accepts visible and near-infrared images. Using the proposed system, images were acquired at 30 fps at both wavelengths, and photoplethysmography signals were extracted by specifying a specific region in the images.

Real-Time Monitoring of Colorectal Cancer Location and Lymph Node Metastasis and Photodynamic Therapy Using Fucoidan-Based Therapeutic Nanogel and Near-Infrared Fluorescence Diagnostic-Therapy System.

We report real-time monitoring of colorectal cancer, lymph node metastasis of colorectal cancer cells, and tumor growth inhibition through photodynamic therapy (PDT) using a near-infrared fluorescence diagnostic-therapy system with a light source for PDT and a fucoidan-based theranostic nanogel (CFN-gel) with good accumulation efficiency in cancer cells. To confirm the effect of the fabricated system and developed CFN-gel, in vitro and in vivo experiments were performed. Chlorin e6 (Ce6) and 5-aminolevulinic acid (5-ALA) were used for comparison.