Publications by authors named "You-Jie Liu"
Rotator cuff tear (RCT) is a common tendon injury, but the mechanisms of tendon healing remain incompletely understood. Elucidating the molecular mechanisms of tenogenic differentiation is essential to develop novel therapeutic strategies in clinical treatment of RCT. The long noncoding RNA H19 plays a regulatory role in tenogenic differentiation and tendon healing, but its detailed mechanism of action remains unknown.
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- The study aimed to create a diabetes-osteoarthritis (DM-OA) mouse model to confirm that diabetes worsens osteoarthritis and investigate the impact on subchondral bone properties.
- Mice were divided into three groups (DM-OA, OA, and sham), with assessments of blood glucose, body weight, food intake, and various biochemical markers for bone metabolism.
- Results showed that the DM-OA group had elevated markers of bone turnover, altered calcium and osteocalcin levels, and significant deterioration in bone structure and strength compared to the other groups.
BACKGROUND The aim of this study was to assess inflammatory cytokines levels in synovial fluid (SF) before and after electroacupuncture (EA) treatment and to explore whether these biomarkers are associated with function of rotator cuff tear (RCT) patients. MATERIAL AND METHODS We recruited 54 patients with RCT and separated them into an EA group and a control group. The SF biomarker levels were detected at baseline and at 6-week and 6-month follow-up.
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