Publications by authors named "You Mei Xu"

Article Synopsis
  • Cyclophosphamide (CP) is an anticancer drug that can cause significant reproductive toxicity, prompting a study on the protective effects of Chlorogenic acid (CGA) against this damage in mice.
  • The research involved analyzing hormone levels, semen quality, and testicular tissue for oxidative stress markers and gene expression to assess the impact of CGA treatment.
  • Results showed that CGA improved hormone levels, reduced oxidative stress, enhanced sperm quality, and restored testicular cell morphology, indicating CGA's potential to protect against CP-induced reproductive harm.
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Article Synopsis
  • * Researchers found that SNP rs11200647 had a significant association with myopia, particularly moderate myopia, and that other SNPs also showed nominal associations.
  • * The results imply that there may be shared genetic factors between myopia and age-related macular degeneration (AMD), providing new insights into the genetics of myopia.
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Aim: To analyze the impact of the coronavirus disease-2019 (COVID-19) pandemic on the presentation and characteristics of patients hospitalized for ocular trauma in a tertiary hospital in China between 2019 and 2020.

Methods: A retrospective case study was designed to collect information on all cases of ocular trauma in a tertiary hospital from 2019 to 2020 and compare differences in inpatients' data (age, sex, admission vision acuity, type of diagnosis, hospital stays, mechanism of injury and location of injury).

Results: The total number of patients admitted to the Ophthalmology Department was 883 (mean 73.

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