Publications by authors named "You Hyun Yoon"
Biol Pharm Bull
December 2015
Article Synopsis
- Researchers developed a mixed micelle formulation to improve the low oral bioavailability of morin, using a specific ratio of pharmaceutical excipients.
- In rat studies, the new formulation increased morin's bioavailability from 0.4% to 11.2% without affecting its clearance or half-life.
- The formulation also enhanced intestinal absorption by inhibiting P-glycoprotein (P-gp) transport, leading to greater permeability and concentration of morin in the bloodstream.
