Publications by authors named "Yotaro Takaesu"

Objective: To evaluate the efficacy of gasless reduced-port laparoscopic surgery (GRP-LS) using a subcutaneous abdominal wall lifting method for gynecological diseases.

Methods: This study included gasless laparoscopic surgeries performed at our hospital between September 1, 1993 and December 31, 2016. The new GRP-LS technique was compared with the conventional gasless three-port laparoscopic surgery (G3P-LS), based on patient background, operative results in patients treated for laparoscopic myomectomy (LM), laparoscopic ovarian cystectomy (LC), and laparoscopic salpingectomy (LT).

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Previous in vitro studies have suggested that calreticulin (CALR), which is responsible for the folding and quality control of glycoproteins, may be associated with decidualization. However, its precise role in regulating decidualization has not been explored in vivo. Here, we used pregnant rat models to examine endometrial CALR expression during the peri-implantation period.

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MicroRNA (miRNA) expression is altered in cancer cells and is associated with the development and progression of various types of cancer. Accordingly, miRNAs may serve as diagnostic or prognostic biomarkers in cancer patients. In this study, we attempted to analyze circulating exosomal miRNA in patients with cervical cancer.

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Article Synopsis
  • - The study aimed to assess which postoperative therapy, either dienogest or goserelin, is more effective in preventing the recurrence of endometriosis after surgery, as there's no established consensus on hormone therapy treatments.
  • - Researchers conducted a 24-month randomized study with 198 endometriosis patients divided into three groups: those receiving dienogest, those receiving goserelin, and a non-treatment group, measuring recurrence rates, menstrual pain, and side effects.
  • - Results showed that while both medications improved pain, only dienogest significantly reduced recurrence compared to the non-treatment group, making it a more favorable long-term option over goserelin, which had more noticeable side effects.
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