Publications by authors named "Yosuke Okui"

Article Synopsis
  • Ovarian cancer (OC) is a critical health issue as it often goes undiagnosed until advanced stages, leading to poor outcomes due to extensive disease spread.
  • Researchers analyzed ovarian cancer tissues and control samples using advanced techniques to identify changes in 130 metabolites, finding significant alterations, especially in glycometabolism pathways.
  • The study also showed that metabolites like N,N-diacetylspermine were elevated in biofluids such as plasma and urine from OC patients, suggesting potential biomarkers for early detection and understanding of OC metabolic dysregulation.
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Background: Group A streptococcus infection during pregnancy can be concerning. It may cause toxic shock syndrome, which can be fatal. Here, we report a rare case of a pregnant woman who developed infectious sacroiliitis due to group A streptococcus infection.

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Objective: The purpose of our study was to conduct a detailed survey of radical hysterectomy in Japanese patients with early-stage cervical cancer, and to compare oncologic outcomes between open and minimally invasive radical hysterectomy.

Methods: In Japan during 2015, the medical records of 929 patients with FIGO stage IB1 and IIA disease treated with radical hysterectomy were retrospectively reviewed. We assessed patients' characteristics, disease-free survival (DFS), overall survival (OS) and prognostic factors for survival.

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