Publications by authors named "Yosuke Iwasa"
Article Synopsis
- The study explored how the COVID-19 pandemic affected the diagnosis and treatment of colorectal cancer (CRC) by comparing patient data before and during the pandemic.* -
- Findings showed a significant decrease in positive fecal occult blood tests and patients took longer to seek medical help for symptoms during the pandemic, even though the stage of cancer remained unchanged.* -
- Despite patients being hesitant to seek treatment, healthcare practitioners' behavior stayed consistent, resulting in no significant differences in overall survival or recurrence-free survival rates.*
A tailgut cyst is a rare, developmental cyst occurring in the presacral space. Although primarily benign, malignant transformation is a possible complication. Herein, we report a case of liver metastases after resection of a neuroendocrine tumor (NET) arising from a tailgut cyst.
View Article and Find Full Text PDFCronkhite-Canada syndrome (CCS) is a non-hereditary disorder characterized by non-neoplastic gastrointestinal polyposis and ectodermal changes. While corticosteroids are considered effective, some cases are refractory. A 48-year-old woman presented with diarrhea, anorexia, and epigastralgia lasting for 3 months.
View Article and Find Full Text PDFA 70-year-old man underwent surveillance colonoscopy following surgery for occlusive sigmoid colon cancer. The procedure revealed nine sessile serrated lesions (SSLs), including three inverted lesions. Endoscopic and surgical resections were performed.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the characteristics of tumor cells that are exfoliated during colorectal endoscopic submucosal dissection (ESD) and their potential to cause local recurrence.
- Researchers collected samples from 19 patients post-ESD and analyzed gene mutations in both primary tumors and exfoliated cells, finding high concordance in mutations.
- Results indicated that while these exfoliated cells had survival-promoting mutations and remained viable for extended periods, treatment with a 2.0% povidone-iodine solution effectively reduced their viability.
Purpose: To evaluate the effect of mild renal dysfunction on the clinical course after colectomy in patients with colon cancer.
Methods: The subjects of this retrospective study were 263 patients who underwent surgical resection for colon cancer at our hospital between 2011 and 2015. Renal function was assessed based on preoperative estimated glomerular filtration rate (eGFR) values.
Article Synopsis
- Lateral lymph node (LLN) metastasis is a major cause of local recurrence in lower rectal cancer, and current methods can't predict it before surgery.
- A study reviewed data from 102 patients who underwent surgery and imaging to find a relationship between the middle rectal artery (MRA) and LLN metastasis, with notable findings by two expert radiologists.
- The study found that the presence of MRA is a strong predictor of LLN metastasis, with high sensitivity and negative predictive value, suggesting it can help guide treatment strategies for affected patients.
Article Synopsis
- About 30% of colorectal cancer patients develop liver metastases, and this study focused on the role of CD200, an immunosuppressive molecule, in these cases.
- The study analyzed 110 patients who had curative liver surgeries, dividing them into high-CD200 and low-CD200 groups based on their CD200 expression levels.
- Results showed that patients with high CD200 expression had significantly worse overall survival, suggesting that CD200 is an important factor in predicting outcomes and could be targeted for therapy in colorectal liver metastases.
Purpose: Primary tumor location of colon cancer has been reported to affect the prognosis after curative resection. However, some reports suggested the impact was varied by tumor stage. This study analyzed the prognostic impact of the sidedness of colon cancer in stages II, III, and liver metastasis after curative resection using propensity-matched analysis.
View Article and Find Full Text PDFPurpose: The purpose of this study was to evaluate the effectiveness of a wound closure method using a combination of subcuticular sutures and subcutaneous closed-suction drainage (SS closure) for preventing incisional surgical site infection (SSI) in loop ileostomy closure.
Methods: A total of 178 consecutive patients who underwent loop ileostomy closure at Nara Medical University Hospital between 2004 and 2018 were retrospectively assessed. The patients were divided into 2 groups: the conventional skin closure (CC) group from 2004 to 2009 (75 patients) and the SS closure (SS) group from 2010 to 2018 (103 patients).