Needlescopic surgery for broad ligament hernia: A case report.

Broad ligament hernia is a rare type of internal hernia. We herein report a case of broad ligament hernia successfully treated by needlescopic surgery. A 41-year-old woman was referred to our hospital with a complaint of nausea and vomiting.

[A Case of Esophageal Gastrointestinal Stromal Tumor Resected by Mediastinoscope-Assisted Transhiatal Esophagectomy].

A 58-year-old man was followed up for esophageal submucosal tumor at our hospital. Esophagogastroduodenoscopy showed the tumor was located on the left side of the thoracic esophagus and had gradually increased in size. Endoscopic ultrasonography revealed an 18×11.

Functional analysis and clinical significance of sodium iodide symporter expression in gastric cancer.

Background: Recent studies have described important roles for the sodium iodide symporter (NIS) in tumor behavior. The objectives of the present study were to investigate the role of NIS in the regulation of genes involved in tumor progression and the clinicopathological significance of its expression in gastric cancer (GC).

Methods: In human GC cell lines, knockdown experiments were conducted using NIS siRNA, and the effects on proliferation, survival, and cellular movement were analyzed.

Na+/H+ exchanger 1 has tumor suppressive activity and prognostic value in esophageal squamous cell carcinoma.

Na+/H+ exchanger 1 (NHE1) is a plasma membrane transporter that controls intracellular pH and regulates apoptosis and invasion in various cancer cells. However, the function of NHE1 in esophageal squamous cell carcinoma (ESCC) cells and the relationship between the expression of NHE1 and prognosis of ESCC remain unclear. We found that the knockdown of NHE1 in ESCC cells inhibited apoptosis and promoted cell proliferation, migration, and invasion and showed increases in Snail, β-catenin, and activation of PI3K-AKT signaling, which was consistent with the results obtained from microarrays.

[A case of mediastinal recurrence of esophageal cancer diagnosed by endobronchial ultrasound-guided transbronchial needle aspiration].

A 63-year-old man was admitted to our hospital for treatment of cervical esophageal cancer and hepatocellular carcinoma. He had undergone subtotal esophagectomy for esophageal cancer and partial hepatectomy for hepatocellular carcinoma after preoperative chemotherapy and transcatheter arterial embolization (TAE). Histologically, esophageal cancer was diagnosed as pT3, pN2, M0, pStage III.

[Minimally invasive surgery for cancer arising in a reconstructed gastric tube after esophagectomy based on evaluation of blood and lymphatic flow by indocyanine green fluorescence imaging].

A 69-year-old man was admitted to our hospital for treatment of gastric tube cancer detected by screening upper gastrointestinal endoscopy. Seven years previously, he had undergone subtotal esophagectomy for esophageal cancer with gastric pull-up via the retrosternal route. Contrast study revealed a filling defect in the distal part of the reconstructed gastric tube.

[Two cases of surgical resection of rectal gastrointestinal stromal tumor after neoadjuvant therapy with imatinib mesylate].

Case 1: A 58-year-old man who initially presented with diarrhea was diagnosed with rectal gastrointestinal stromal tumor (GIST). The patient initially received neoadjuvant therapy with imatinib mesylate. After imatinib therapy( 400 mg/day) for 23 weeks, the patient's abdominal computed tomography (CT) and magnetic resonance imaging (MRI) scans showed a reduction of approximately 67% in tumor size.