Lactate, choline, and creatine levels measured by vitro 1H-MRS as prognostic parameters in patients with non-small-cell lung cancer.

Purpose: To determine the biochemical characteristics of lung cancer tissue using in vitro (1)H-MRS, and investigate the correlation between survival probabilities and lactate (Lac), creatine (Cr), and choline (Cho) concentrations measured by in vitro (1)H-MRS.

Materials And Methods: A total of 21 patients with lung cancer were included in this retrospective study. (1)H-MRS spectra measurements were performed at 6.

In-vitro 1H-MRS of excised rabbit lung: evaluation of preservation method of the lung using 10% DMSO solution.

Purpose: This study was performed to investigate the lactate, creatine, and choline changes in excised rabbit lung metabolites using proton magnetic resonance spectroscopy (1H-MRS).

Materials And Methods: Rabbit lung was preserved with -20 degrees C 10% dimethyl sulfoxide (DMSO) solution until used, and the lactate, creatine, and choline levels of the rabbit lung were evaluated by 1H-MRS (6.34T superconducting unit).

In vitro proton magnetic resonance spectroscopic lactate and choline measurements, 18F-FDG uptake, and prognosis in patients with lung adenocarcinoma.

Unlabelled: It has been reported that (18)F-FDG uptake, lactate concentration, and choline concentration are good indicators of malignant grade in several different kinds of tumors. In this study, we investigated the correlation between (18)F-FDG uptake in (18)F-FDG PET imaging, lactate concentration and choline concentration measured by in vitro (1)H magnetic resonance spectroscopy (MRS), and survival probabilities in human lung adenocarcinoma.

Methods: Nineteen patients with lung adenocarcinoma underwent (18)F-FDG PET before surgery.

Definitive expression of c-mos in late meiotic prophase leads to phosphorylation of a 34 kda protein in cultured rat spermatocytes.

To investigate the role of c-mos in rat spermatogenesis, expression of c-mos, MAP kinase kinase (MAPKK), MAP kinase (MAPK), cdc2 and protein kinase A (PKA) by spermatogenic cell culture of 14 day-old rats was examined. MAPKK and PKA expressions were constitutive, whereas the expression of MAPK and cdc2 in spermatogonia initially decreased, but later increased on meiotic maturation of spermatocytes. c-mos expression was definitive of late meiotic prophase.