Background: In rheumatoid arthritis (RA), matrix metalloproteinase-3 (MMP-3) and oxidative stress contribute to joint destruction. However, little is known about the relationship between MMP-3 and oxidative stress in RA.
Methods: We measured the albumin-thiol redox state as a marker of oxidative stress, MMP-3, and the DAS-28 score calculated using CRP values among forty-seven patients (9 males and 38 females) with RA.
We report a rare case of closed rupture of both flexor digitorum profundus (FDP) and flexor digitorum superficialis tendons in zone II in the small finger. We performed delayed, primary end-to-end suture of the FDP and excision of the flexor digitorum superficialis, because myostatic contracture of the FDP tendon was not severe and the FDP tendon remnants were not frayed.
View Article and Find Full Text PDFArch Orthop Trauma Surg
April 2009
Study Design: A case report and a biomechanical study using a finite element method.
Objectives: To report a case with the cervical spondylolysis and to understand the biomechanics of the cervical spine with spondylolysis at C6. Cervical spondylolysis, although not a common spinal disorder, can occur in athletes.
Background: It is well known that anterior cruciate ligament (ACL) injuries are commoner in female athletes. Accordingly, we hypothesized that serum estrogen may play some role in this sex difference. We evaluated the relationship between serum estrogen levels and the mechanical properties of the ACL in rabbits.
View Article and Find Full Text PDFFour knees in three patients with traumatic separation of a Type I bipartite patella are reported. Sudden anterior knee pain and an audible pop occurred at the time of the injury and the patients had aching or dull pain before the traumatic episode. Previous aching or dull pain led us to differentiate this type of injury from a usual transverse fracture.
View Article and Find Full Text PDFClin Orthop Relat Res
September 2003
Five patients with pigmented villonodular synovitis of the knee associated with lesions of the posterior periarticular bursae were treated by posterior exploration, excision of the bursal tissue, and routine anterior synovectomy of the knee. It was hypothesized that complete excision of the posterior periarticular bursae would reduce the high recurrence rate of pigmented villonodular synovitis of the knee. To completely excise the periarticular lesions, two posterior oblique skin incisions were used.
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