Publications by authors named "Yoshitomo Okajima"

Background: Working is an important concern in transitional care for adults with congenital heart disease (ACHD) because work connects people with society. Employment status is correlated with gender, but studies on patient employment by gender have rarely been conducted. This study therefore aimed to examine the employment status of ACHD by gender and to explore the factors influencing this status.

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Background: Genetic studies have indicated possible involvement of the upregulated calcium-nuclear factor of activated T cells pathway in the pathogenesis of Kawasaki disease. We aimed to assess safety and efficacy of ciclosporin, an immunosuppressant targeting this pathway, for protection of patients with Kawasaki disease against coronary artery abnormalities.

Methods: We did a randomised, open-label, blinded endpoints trial involving 22 hospitals in Japan between May 29, 2014, and Dec 27, 2016.

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The number of the adult patients with congenital heart diseases (ACHD) continues to grow owing to improvement of surgical results and medical management. Corrective surgery for complex CHD does not always mean complete cure. It is not rare that the patients will visit the cardiology institutes because of secondary lesions due to residua or sequela in adults.

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Article Synopsis
  • A 13-year-old girl was diagnosed with vasospastic angina post-mortem, after experiencing recurrent toothaches since she was 10.
  • Despite normal evaluations at a medical center, she suffered a severe toothache and later collapsed at school, leading to her death.
  • Autopsy revealed significant coronary artery issues and multiple heart tissue injuries, indicating that her toothache was a symptom of a serious underlying heart condition, highlighting that vasospastic angina can affect young individuals and lead to sudden cardiac events.
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