Publications by authors named "Yoshitomo Fukuoka"

Don't blindly accept the automated assessment of electrocardiogram. It is important to raise long QT syndrome to the differential diagnosis of repeated syncope.

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  • This study investigates the impact of catheter ablation on various biomarkers, particularly focusing on uric acid (UA), glucose, and lipid metabolism in atrial fibrillation (AF) patients.
  • A total of 206 AF patients were analyzed, showing significant decreases in both uric acid and brain natriuretic peptide (BNP) levels one year after the procedure, with persistent AF patients experiencing a more notable decline in UA levels.
  • The findings suggest that ablation is effective in improving UA levels in AF patients without negatively affecting heart function or kidney health, indicating its potential benefits for those with high UA levels prior to the procedure.
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  • Left atrial roof-dependent tachycardias (LARTs) are a type of atrial tachycardia that can be effectively studied using advanced mapping systems in patients.
  • In a study of 22 LARTs among 21 patients, researchers found that different types of prior cardiac interventions influenced the characteristics and management of these tachycardias.
  • The study revealed varied mechanisms for LARTs, with a high success rate for eliminating these arrhythmias during treatment, particularly when all related arrhythmias were addressed.
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The diagnosis of cardiac amyloidosis is frequently delayed because histological confirmation is often challenging. Few studies have attempted to clarify the utility and safety of abdominal fat pad fine-needle aspiration (FPFNA) for an initial screening test in patients with suspected cardiac amyloidosis.This study included 77 consecutive patients with suspected non-ischemic cardiomyopathy who had left ventricular dysfunction and/or hypertrophy.

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Objectve To assess the impact of glycemic variability on blood pressure in hospitalized patients with cardiac disease. Methods In 40 patients with cardiovascular disease, the glucose levels were monitored by flash continuous glucose monitoring (FGM; Free-Style Libre™ or Free-Style Libre Pro; Abbott, Witney, UK) and self-monitoring blood glucose (SMBG) for 14 days. Blood pressure measurements were performed twice daily (morning and evening) at the same time as the glucose level measurement using SMBG.

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Background: Low voltage areas (LVAs) are most commonly observed on the left atrial (LA) septal/anterior wall.

Objective: We explored the mechanisms of LA septal/anterior wall reentrant tachycardias (LASARTs) using ultrahigh resolution mapping.

Methods: This study included seven consecutive LASARTs in six patients (75 [62.

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Reported mapping procedures of left atrial (LA) low-voltage areas (LVAs) vary widely. This study aimed to compare the PentaRay/CARTO3 (PentaRay map) and Orion™/Rhythmia™ (Orion map) systems for LA voltage mapping. This study included 15 patients who underwent successful pulmonary vein isolation (PVI) for atrial fibrillation.

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Background: An association between early repolarization and ventricular fibrillation has recently been reported in patients with vasospastic angina (VSA). However, no studies have clarified whether the presence of early repolarization can predict VSA.

Methods: Participants comprised 286 patients (136 males) with clinically suspected VSA who underwent intracoronary provocation tests using acetylcholine or ergonovine.

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Background: Detailed mapping studies of accessory pathway (AP) conduction have not been previously performed using ultra-high resolution mapping systems. We sought to evaluate the clinical utility of ultra-high resolution mapping systems and the novel "Lumipoint" algorithm in AP ablation.

Methods: This study included 17 patients who underwent AP mapping using minielectrode basket catheters and Rhythmia systems.

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Background: Perimitral atrial tachycardias (PMATs) are common atrial tachycardias (ATs), yet their mechanisms vary.

Objective: The purpose of this study was to characterize clinical spontaneous PMATs using an ultra-high-resolution (UHR) mapping system.

Methods: The study included 32 consecutive PMATs in 31 patients who had undergone AT mapping/ablation using a UHR mapping system.

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Aim: The aim of this study was to examine the effects of evolocumab on favorable limb events in patients with chronic limb-threatening ischemia (CLTI).

Methods: A single-center, prospective observational study was performed on 30 patients with CLTI. The subjects were divided into 2 groups based on evolocumab administration: evolocumab-treated (E) group ( n=14) and evolocumab non-treated (non-E) group (n=16).

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Background: Few studies have examined the characteristics of catheter ablation vascular complications, and recently physicians increasingly use computed tomography angiography (CTA) for diagnosing.

Objective: We sought to investigate the incidence of femoral vascular complications in catheter ablation and factors associated with complications in the current era.

Methods: This single-center observational study consisted of 311 consecutive (atrial fibrillation, atrial flutter, paroxysmal supraventricular tachycardia, and ventricular arrhythmias in 222 [71.

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Article Synopsis
  • Left ventricular (LV) systolic dysfunction can improve in some patients after controlling arrhythmias like atrial fibrillation and flutter, but recognizing this condition is difficult.
  • In a study of 40 patients undergoing catheter ablation, those with improved LV ejection fraction (LVEF) post-procedure had significant increases in heart function over time, with 75% showing recovery.
  • High-sensitivity troponin T levels before the procedure were found to be a reliable predictor of improving LV dysfunction, indicating that lower levels (≤12 pg/mL) could effectively signal potential recovery post-ablation.
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  • The study evaluates the effectiveness of cryothermal ablation for creating linear lesions in patients with atrial fibrillation, comparing it to traditional radiofrequency ablation.
  • Results showed that cryoablation successfully created conduction block in most targeted areas, but had challenges in achieving block at the mitral isthmus, especially when anatomical variations were present.
  • After follow-up, cryoablation patients experienced a higher rate of freedom from atrial fibrillation and fewer recurrent atrial tachycardias compared to those treated with radiofrequency ablation.
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Aims: The sequential organ failure assessment (SOFA) score has been a widely used predictor of outcomes in the intensive care unit, whereas short-term and long-term survivals of heart failure (HF) patients are predicted by the American Heart Association Get With the Guidelines-Heart Failure (GWTG-HF) risk score. The purpose of present study was to examine whether the SOFA score on admission is more useful for predicting long-term mortality in acute HF patients than the GWTG-HF risk score.

Methods And Results: A total of 269 patients (mean age, 78.

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Background: Fibro-inflammatory processes in the extracellular matrix are closely associated with progressive structural remodeling in atrial fibrillation (AF). Serum concentrations of tenascin-C (TNC), an extracellular matrix glycoprotein, and of high-sensitivity C-reactive protein (CRP) might serve as a marker of remodeling and progressive inflammation of the aorta and in myocardial diseases. This study aimed to clarify relationships between TNC and CRP in patients with AF.

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Uninterrupted anticoagulation therapy during atrial fibrillation (AF) ablation minimizes the risk of periprocedural thromboembolic events. Although the use of direct oral anticoagulants (DOACs) has rapidly developed in patients undergoing AF ablation, no antidote is available for factor Xa inhibitors. We sought to investigate the feasibility of an uninterrupted DOAC protocol with temporary switching to dabigatran ("dabigatran bridge") for AF ablation.

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Atrial tachyarrhythmias often originate from the superior vena cava (SVC), and right superior (RSPV) and inferior pulmonary veins (RIPV). However, a precise differentiation of those origins is challenging using the standard 12-lead electrocardiogram (ECG) P-wave morphology due to the anatomical proximity. The recently developed synthesized 18-lead ECG provides virtual waveforms of the right-sided chest and back leads.

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Background: The utility of pressure waveform analyses to assess pulmonary vein (PV) occlusions has been reported in cryoballoon PV isolation (CB-PVI) using first-generation CBs. This prospective randomized study compared the procedural and clinical outcomes of pressure-guided and conventional CB-PVI.

Methods And Results: Sixty patients with paroxysmal atrial fibrillation underwent CB-PVI with 28-mm second-generation CBs.

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Background: The oral vasopressin-2 receptor antagonist, tolvaptan, causes aquaresis and improves symptoms in patients with congestive heart failure. However, few studies have explored the effect of tolvaptan in acute heart failure (AHF) patients ≥90 years old.

Methods: This study enrolled 106 AHF patients treated with tolvaptan added to standard therapy.

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Objective Circulating endothelial progenitor cells (EPCs) are regulated by stromal cell-derived factor-1alpha (SDF-1α) and are reduced in type 2 diabetes mellitus (DM). SDF-1α is a substrate of dipeptidyl-peptidase-4 (DPP-4), so we investigated whether or not DPP-4-inhibitors modulate EPC levels in type 2 DM patients with coronary artery disease (CAD). Methods Thirty patients with CAD and type 2 DM treated using an ordinary regimen were enrolled.

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Cavo-tricuspid isthmus (CTI) anatomies are highly variable, and specific anatomies lead to a difficult CTI ablation. This study aimed to compare the clinical utility of angiography and intracardiac echocardiography (ICE) in evaluating CTI anatomies, and to investigate the impact of the CTI anatomy on the procedure when the ablation tactic was adjusted to the anatomy. This study included 92 consecutive patients who underwent a CTI ablation.

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The number of implantations of cardiac implantable electrophysiological devices (CIEDs) has increased over the past several years. However, the aging population and expansion of indications for CIEDs have led to an increase in associated infections. We experienced a case of a 99-year-old man presenting with skin erosion at the pocket site, where a 6-month-old implantable pacemaker was replaced.

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