Publications by authors named "Yoshitaka Sugawara"

57-year-old man with bilateral giant lung bullae was admitted to our hospital for dyspnea on exertion as his chief complaint. The size and shape of right lung bullae were bigger and more complicated than those of left lung bullae. He underwent 2-staged bullectomy by video-assisted thoracoscopic surgery (VATS).

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  • Previous studies indicated that right ventricular pacing can lead to pacing-induced cardiac dysfunction (PICD), prompting this investigation into clinical characteristics and the occurrence of undiagnosed cardiac sarcoidosis (CS) in patients with atrioventricular block (AVB) showing PICD.
  • Researchers analyzed patients with permanent pacemakers who underwent generator replacement from 2011 to 2017; they were divided into two groups based on their left ventricular ejection fraction post-PPM installation.
  • Findings revealed a higher incidence of cardiac sarcoidosis in the PICD group (46.7% diagnosed post-PPM) despite none having been recognized prior to pacemaker placement.
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A 74-year-old woman who developed atrial tachycardia following the Cox-Maze IV procedure underwent catheter ablation. The reentrant circuit included the coronary sinus (CS), Marshall bundle (MB), distal MB-left atrial (LA) connection, and anterolateral mitral annulus. The distal MB-LA connection was the last barrier in the conduction pathway between the CS and the left atrium.

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Atrial fibrillation (AF) is one of the most common cardiac arrhythmias, and carries an increased risk of cardiogenic embolism. Oral anticoagulants (OACs) including warfarin and/or non-vitamin K antagonists can prevent the majority of these events. The Saitama AF Registry was a community-based survey of patients with AF in Saitama City, which represents an urban community in Japan.

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Objectives: The aim of this study was to determine whether re-entrant circuits were associated with the ligament of Marshall (LOM).

Background: Peri-mitral atrial tachycardias (PMATs) following pulmonary vein isolation (PVI) or mitral valve surgery are common.

Methods: Six PMATs involving epicardial circuits were identified from 38 patients.

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  • The study investigates the effectiveness of diastolic pulmonary vascular pressure gradient (DPG) versus transpulmonary pressure gradient (TPPG) in identifying pulmonary hypertension (PH) associated with left heart disease (LHD) in patients with pulmonary vascular disease (PVD).
  • Among 410 patients with heart failure analyzed, 40% were found to have PH-LHD, with 3% classified in the DPG-PVD group and 6% in the TPPG-PVD group.
  • The DPG-PVD group showed a significant association with higher risks of death and heart failure readmission compared to the Non-PVD group, while the TPPG-PVD group's association was not statistically significant, indicating DPG
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Diabetes mellitus and impaired glucose tolerance are well-known risk factors for coronary artery disease (CAD) and adverse clinical events after percutaneous coronary intervention (PCI). Postprandial hyperglycemia is an important risk factor for CAD and serum 1,5-anhydroglucitol (1,5-AG) reflects postprandial hyperglycemia more robustly than hemoglobin (Hb)A1c. We aimed to clarify the relationship between serum 1,5-AG level and adverse clinical events after PCI.

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Acute aortic dissection (AAD) is a life-threatening cardiovascular disease with high mortality. Hypertension is a well known risk factor of AAD. There have been previous reports about the association between circadian variation of blood pressure (BP) and cardiovascular events.

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Background: Peripheral venoarterial extracorporeal membranous oxygenation (ECMO) support is effective in patients with cardiogenic shock or fatal arrhythmia due to fulminant myocarditis. The clinical courses of fulminant myocarditis are still uncertain; therefore, it is difficult to determine the appropriate time for discontinuing ECMO or converting to a ventricular assist device. The purpose of this study was to investigate the prognosis of patients with fulminant myocarditis managed by ECMO.

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Background: The perioperative risk of non-cardiac surgery (NCS) in the patients on antiplatelet therapy after percutaneous coronary intervention (PCI) remains unclear.

Methods: This study was a retrospective and single center study. Between January 2008 and December 2011, 198 patients who had already received PCI underwent NCS in our hospital.

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  • Dipeptidyl peptidase-4 (DPP4) is a protein involved in diabetes management, with DPP4 inhibitors emerging as a treatment option for type-2 diabetes.
  • Recent studies suggest that these inhibitors may enhance heart function post-heart attack, specifically after acute myocardial infarction (AMI) in diabetic patients.
  • A study on 34 diabetic patients showed that those treated with DPP4 inhibitors had significant improvements in cardiac function metrics compared to those who didn’t receive the inhibitors, indicating potential benefits for heart health.
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Postprandial hyperglycemia is a risk factor for cardiovascular disease and mortality. Serum 1,5-anhydroglucitol (1,5-AG) level is an useful clinical marker of glucose metabolism which reflects postprandial hyperglycemia more robustly compared to hemoglobin A1c (HbA1c). Relationship between serum 1,5-AG level and cardiovascular disease has been reported; however, comparison between HbA1c and 1,5-AG as markers of cardiovascular disease was not performed.

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Early statin treatment of patients with acute coronary syndrome results in vascular changes and improved clinical outcomes. However, the influence of chronic statin treatment on the culprit vessel in acute coronary syndrome is not fully understood. The aim of this study was to investigate the morphologic features of the culprit vessel in acute myocardial infarction by comparing patients with and without chronic statin treatment.

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Background: The circumstances surrounding infective endocarditis (IE) are under constant change due to an increase in drug-resistant organisms, a decrease in rheumatic valve disease, progress in surgical treatment, and aging society. The purpose of this study was to compare clinical features of IE between the 1990s and 2000s and to elucidate the determinants of death or clinical event.

Methods: All hospital admission records between January 1990 and December 2009 were retrospectively analyzed.

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  • No reflow is a significant complication after primary percutaneous coronary intervention (PCI) in treating heart attacks, with some cases being reversible (transient) and others not (persistent).
  • The study involved 123 patients with no reflow, comparing those with transient (59 patients) and persistent (64 patients) no reflow to identify clinical features and outcomes.
  • Findings revealed that those with transient no reflow had a lower in-hospital cardiac death rate and potential predictors for recovery include good initial blood flow (TIMI grade 3) and better kidney function (as indicated by glomerular filtration rate).
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Clinical features and outcomes of acute myocardial infarction (AMI) in the young have been poorly investigated. The aim of this study was to investigate the clinical features and hospital outcomes of AMI in young Japanese. We conducted a case-control study.

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Intravascular lymphomatosis (IVL) is a rare subtype of lymphoma characterized by proliferation of lymphoma cells into small vessels. Clinical presentations of IVL are considerably varied among patients, and antemortem diagnosis is sometimes difficult. We report a 75-year-old Japanese female who presented with gradually worsening shortness of breath and pulmonary hypertension.

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Contrast media affects renal function, especially in the patients with advanced chronic kidney disease (CKD). The aim of this study was to investigate the characteristics of contrast induced exacerbation of renal dysfunction in the patients with advanced CKD (estimated glomerular filtration rate <30 ml/min/1.73 m(2)).

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  • Left ventricular apical aneurysm (LVAA) is a serious complication following acute anterior myocardial infarction, and this study examined its clinical features in patients treated with primary PCI.
  • A total of 161 patients with acute anterior MI who underwent primary PCI were studied, with 18% developing LVAA in the chronic phase.
  • Key predictors for LVAA included peak CK levels, discharge heart rate, and poor final TIMI flow and myocardial brush grades, suggesting that achieving a TIMI flow grade of 3 during primary PCI may help prevent LVAA.
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Fractional flow reserve (FFR) is considered as the gold standard for physiological assessment of coronary artery stenosis. However, it may be difficult to interpret FFR for the stenosis of the donor artery of chronic total occlusion (CTO), because revascularization of CTO may improve FFR of the donor artery. We present a case of 32-year-old male who had a CTO in right coronary artery (RCA), 90% stenoses in left circumflex artery (LCx) and a mild stenosis in the middle segment of left anterior descending artery (LAD).

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