Publications by authors named "Yoshitaka Matsuura"

Article Synopsis
  • Traditional wound dressings may not effectively treat chronic wounds due to bacterial growth, leading researchers to explore silk-elastin solutions as a potential alternative for promoting healing.
  • A clinical case series conducted on 6 patients with chronic skin ulcers at Kyoto University Hospital tested silk-elastin sponges covered with a polyurethane film over 14 days, monitoring for adverse events.
  • While some patients experienced treatment discontinuation due to inflammation, no serious infections were reported, suggesting silk-elastin sponges are safe and warrant further clinical trials to confirm their effectiveness in wound healing.
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Although primary surgery for cleft lip has improved over time, the degree of secondary cleft or nasal deformity reportedly varies from a minimum degree to a remarkable degree. Patients with cleft often worry about residual nose deformity, such as a displaced columella, a broad nasal floor, and a deviation of the alar base on the cleft side. Some of the factors that occur in association with secondary cleft or nasal deformity include a deviation of the anterior nasal spine, a deflected septum, a deficiency of the orbicularis muscle, and a lack of bone underlying the nose.

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Background: Giant congenital melanocytic nevi (GCMN) treatment remains controversial. While surgical resection is the best option for complete removal, skin shortage to reconstruct the skin defect remains an issue. We report a novel treatment using a high hydrostatic pressurization (HHP) technique and a cryopreservation procedure.

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Purpura fulminans is a rare disease that usually causes sepsis and is accompanied by disseminated intravascular coagulation and symmetric gangrene of distal extremities. We had to consider the most appropriate surgery approach. The most important point was attempting to rescue the patient's ability to walk under his own power.

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The wounds of full- and deep partial-thickness burns result in hypertrophic scars and lead to skin contracture more severely than those of superficial partial-thickness burns. Therefore, preventing burn progression may help improve the aesthetic and functional outcomes after healing. Although a number of studies have focused on elucidating the underlying mechanisms of and preventing burn wound progression, it is still difficult to rescue burned dermis unless early tangential excision is performed.

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Cutaneous ulcers are treated with dressing materials and/or ointments to keep the wound in an appropriately moist environment. However, chronic cutaneous ulcers commonly have bacterial colonization that can cause local infection in such an environment. Therefore, the dressing materials and/or ointments should have antibacterial potency to treat chronic ulcers.

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Article Synopsis
  • Silk-elastin is a new recombinant protein polymer that combines silk and elastin to promote wound healing through a self-assembling process from liquid to gel.
  • Researchers developed a silk-elastin sponge to address application challenges faced with the aqueous solution in clinical settings.
  • The study found that the silk-elastin sponge effectively promotes granulation tissue formation just like the liquid version, as it dissolves in wound exudate to form a beneficial gel containing cytokines.
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When the lesser palatine nerve (LPN) is supposed to be a branch of the trigeminal nerve and innervate sensation of the soft palate, whether the LPN contains motor fibers is unclear. In this study, we monitored the electromyogram of the levator veli palatini (LVP) muscle on stimulating the LPN during palatoplasty in 3 patients. The electromyogram of the muscles showed the myogenic potential induced by electrostimulation of the LPN.

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The paste form of calcium phosphate cement is often used in skull reconstruction because of the biocompatibility and early handling of these cements. Although it had rarely been shown to produce a foreign body reaction, we encountered a patient who experienced an allergic reaction to calcium phosphate cements(Biopex®. A patch test was performed and a positive reaction to magnesium phosphate was obtained.

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