Comparison of recovery of mobility and self-efficacy after total knee arthroplasty based on two different protocols: A prospective cohort study.

: The purpose of this study was to compare the recovery of mobility and self-efficacy following total knee arthroplasty (TKA) between the 5-day and the 28-day protocol. This prospective cohort study was carried out at two hospitals.: In total, 104 patients who underwent TKA were enrolled.

Total knee arthroplasty for treatment of osteoarthritis with prolonged patellar dislocation.

Prolonged dislocation of the patella is a rare condition and is often related to severe osteoarthritis (OA) of the femorotibial (FT) joint. For this condition's treatment, numerous surgical techniques using total knee arthroplasty (TKA) have been published. To the best of our knowledge, this case report is the first description of the use of lateral release alone to treat recurrent patellar subluxation with TKA.

Lidocaine induces ROCK-dependent membrane blebbing and subsequent cell death in rabbit articular chondrocytes.

Local anesthetics are administered intraarticularly for pain control in orthopedic clinics and surgeries. Although previous studies have shown that local anesthetics can be toxic to chondrocytes, the underlying cellular mechanisms remain unclear. The present study investigates acute cellular responses associated with lidocaine-induced toxicity to articular chondrocytes.

Joint Arthroplasty With Osteochondral Grafting From the Knee for Posttraumatic or Degenerative Hand Joint Disorders.

Purpose: To describe the operative procedure and report the clinical outcomes of articular surface reconstruction for various hand joint disorders using autologous osteochondral grafts from the knee.

Methods: Ten patients underwent articular surface reconstruction for hand joint disorders with autologous osteochondral grafts from the patellofemoral joint. Mean patient age was 35 years (range, 15-52 y).

New option for surgical treatment of the trapeziometacarpal osteoarthritis: a case report.

We present the case of a 71-year-old, left-handed woman with left thumb carpometacarpal (CMC) joint arthritis. The patient had no pain and could use the hand actively in daily life with a new option of surgical treatment, a vascularized pedicled third CMC joint transfer to the thumb CMC joint.

Extracellular and intracellular mechanisms of mechanotransduction in three-dimensionally embedded rat chondrocytes.

Purpose: Articular cartilage homeostasis involves modulation of chondrocyte matrix synthesis in response to mechanical stress (MS). We studied extracellular and intracellular mechanotransduction pathways mediating this response.

Methods: We first confirmed rapid up-regulation of the putative chondro-protective cytokine, interleukin (IL)-4, as an immediate response to MS.

Late-Emerging Lethal Exacerbation of Cardiomyopathy in a Patient with Mitochondrial Myopathy After Total Hip Arthroplasty: A Case Report.

Case: Mitochondrial myopathy comprises heterogeneous neuromuscular disorders caused by mitochondrial dysfunction. Acute exacerbation of mitochondrial myopathy infrequently occurs sequentially after perioperative stress. We present an unusual case of a late-emerging and lethal exacerbation of mitochondrial myopathy after total hip arthroplasty.

Improved quality of cartilage repair by bone marrow mesenchymal stem cells for treatment of an osteochondral defect in a cynomolgus macaque model.

Background And Purpose: Integration of repaired cartilage with surrounding native cartilage is a major challenge for successful tissue-engineering strategies of cartilage repair. We investigated whether incorporation of mesenchymal stem cells (MSCs) into the collagen scaffold improves integration and repair of cartilage defects in a cynomolgus macaque model.

Methods: Cynomolgus macaque bone marrow-derived MSCs were isolated and incorporated into type-I collagen gel.

Operative treatment of metacarpal and phalangeal fractures in athletes: early return to play.

Background: Evaluating the outcomes of operative treatment for metacarpal and phalangeal fractures in athletes returning early to play and discussing the more effective methods that permit rapid early return to athletic activity.

Methods: We retrospectively identified a total of 105 metacarpal or phalangeal fractures in 105 athletes with conservative or operative treatment in our department. Of these, 20 athletes required an early return to sport because of a pending important game in their competition within 1 month after injury.

Comparison of repair between cartilage and osteocartilage defects in rabbits using similarly manipulated scaffold-free cartilage-like constructs.

Background: Articular cartilage has a limited capacity for spontaneous repair, and its repair remains a clinical challenge. The purpose of this study was to prepare scaffold-free cartilage-like constructs and evaluate the feasibility of their use for the treatment of cartilage and osteocartilage defects in vivo.

Methods: The scaffold-free constructs were prepared by chondrocytes isolated from the articular cartilage of rabbits using a high-density three-dimensional culture system.

Ultrasound-assisted closed reduction of distal radius fractures.

Purpose: To assess the accuracy and ability of ultrasound for monitoring closed reduction for distal radius fractures.

Methods: Consecutive patients undergoing ultrasound-guided closed reduction of acute, displaced distal radius fractures between January 2003 and December 2006 at our department were enrolled. The control group was extracted from patients who underwent a closed reduction for similar fractures under fluoroscopy or without any imaging assistance.

Triple pelvic osteotomy: Report of our mid-term results and review of literature.

A wide variety of pelvic osteotomies have been developed for the treatment of developmental dysplasia of the hip (DDH). In the present paper, we present a detailed review of previous studies of triple osteotomy as an alternative treatment for DDH. We also report our experience treating 6 adult cases of DDH by triple osteotomy in order to highlight the various aspects of this procedure.

Prevalence, distribution, and morphology of thoracic ossification of the posterior longitudinal ligament in Japanese: results of CT-based cross-sectional study.

Study Design: A cross-sectional study.

Objective: To gain an insight into the prevalence, morphology, and distribution of thoracic ossification of the posterior longitudinal ligament of the spine (T-OPLL) by computed tomography (CT) and review of the literature.

Summary Of Background Data: The epidemiology and cause of T-OPLL remains obscure.

Immunohistochemical localization of D-serine dehydratase in chicken tissues.

Chicken D-serine dehydratase (DSD) degrades d-serine to pyruvate and ammonia. The enzyme requires both pyridoxal 5'-phosphate and Zn(2+) for its activity. d-Serine is a physiological coagonist that regulates the activity of the N-methyl-d-aspartate receptor (NMDAR) for l-glutamate.

Prevalence, distribution, and morphology of thoracic ossification of the yellow ligament in Japanese: results of CT-based cross-sectional study.

Study Design: A cross-sectional study.

Objective: To gain an insight for the prevalence, morphology, and distribution of thoracic ossification of the yellow ligament (OYL) by computed tomography (CT) and review of the literature.

Summary Of Background Data: The epidemiology and etiology of OYL remains obscure.

Pigmented villonodular synovitis causing osteonecrosis of the femoral head: a case report.

We report a case of a 27-year-old man with pigmented villonodular synovitis of the hip joint with coincident osteonecrosis of the femoral head. According to our review of the English-language literature, no detailed report of osteonecrosis of the femoral head complicated with pigmented villonodular synovitis has been published. Preoperative X-ray images showed joint narrowing and severe multiple bone erosions at the acetabulum and femoral neck.

Acceptable parameters for alignment of distal radius fracture with conservative treatment in elderly patients.

Background: There is a conflict in the treatment of distal radius fractures in elderly patients, because fracture reduction does not appear to be as strongly associated with functional outcomes as in younger patients. The purpose of this study was to evaluate radiographic findings of acceptable reduction without leading to wrist dysfunction and poor outcomes.

Methods: Fifty-two active and healthy elderly patients with conservatively managed distal radius fractures were included in the study.

Long-term clinical outcome of sacral chondrosarcoma treated by total en bloc sacrectomy and reconstruction of lumbosacral and pelvic ring using intraoperative extracorporeal irradiated autologous tumor-bearing sacrum: a case report with 10 years follow-up.

Background Context: Primary malignant tumors of the sacrum are rare. Chondrosarcoma is one of the common malignant tumors arising from the sacrum. Chondrosarcoma is often invasive, and there is a high propensity for local recurrence.

Primary bone carcinosarcoma of the fibula with chondrosarcoma and squamous cell carcinoma components.

Carcinosarcoma is defined as a malignant neoplasm that is composed of both carcinomatous and sarcomatous components. The occurrence of carcinosarcoma in the bone is extremely rare. In this report, we describe the third documented de novo case of carcinosarcoma of the bone.

The COX-2 selective blocker etodolac inhibits TNFα-induced apoptosis in isolated rabbit articular chondrocytes.

Chondrocyte apoptosis contributes to the disruption of cartilage integrity in osteoarthritis (OA). Recently, we reported that activation of volume-sensitive Cl- current (ICl,vol) mediates cell shrinkage, triggering apoptosis in rabbit articular chondrocytes. A cyclooxygenase (COX) blocker is frequently used for the treatment of OA.