Expression and distribution of cyclooxygenase-2 in human ovary during follicular development.

Prostaglandins play important roles for oocyte maturation and follicular rupture. Cyclooxygenase-2 (COX-2), an inducible isoform of a prostaglandin metabolic enzyme, is essential for the timed production of prostaglandins in the ovary. The aim of the present study is to examine expression and distribution of COX-2 in human ovarian follicles at each of the maturation stages.

Clinical features and treatment prognosis of infertile males with robertsonian translocation.

Background: The principle of treating male infertility in those with chromosomal aberrations should change according to progress in treatment modalities.

Methods: In this study, ten patients with Robertsonian translocation were assessed for their cytogenetic and clinical characteristics to establish guidelines for treating these patients.

Results: In 8 of 10 cases, chromosomes 13 and 14 were involved.