Publications by authors named "Yoshio Enyo"
Introduction: Balloon kyphoplasty (BKP) for osteoporotic vertebral fracture (OVF) has been reported to maintain quality of life (QOL). This study aimed to investigate the effectiveness of ultra-early BKP performed within two weeks of injury (ultra-early group) to cases after two to four weeks post-injury (early group) and over four weeks (conventional group), assessing radiographic assessment such as subsequent fracture etc, questionarre such as QOL and back pain-related activities of daily living (ADL) one year after surgery.
Methods: Ninety cases of OVF treated with BKP (23 males, 67 females, average age 78.
Study Design: Retrospective cohort study.
Purpose: Balloon kyphoplasty (BKP) is a minimally invasive surgical treatment for osteoporotic vertebral compression fractures (OVCFs), with good clinical outcomes reported in short-term investigations. However, the impact of BKP on health-related QOL in the long term remains unclear.
Article Synopsis
- Adequate nutrition is crucial for older adults undergoing lumbar surgery, as it helps manage surgical stress and preserve muscle function, but the benefits of amino acids and vitamin D remain unclear.
- This study aimed to determine if supplementing with branched-chain amino acids (BCAA) and vitamin D could reduce muscle loss, improve mobility, and enhance recovery outcomes after surgery for lumbar spinal stenosis (LSS).
- Results showed that while the BCAA group had better knee strength compared to the non-amino acid group at different points post-surgery, there were no significant differences in overall clinical outcomes between the two groups after 12 and 52 weeks.
Background: Although lumbar spinal stenosis (LSS) often coexists with other degenerative conditions, few studies have fully assessed possible contributing factors for low back pain (LBP) in patients with LSS. The purpose of this study was to identify factors associated with the severity of LBP in patients with LSS.
Methods: The patients with neurogenic claudication caused by LSS, which was confirmed by magnetic resonance imaging (MRI) were included in this cross-sectional study.
Background: Previous studies comparing surgical with nonsurgical treatment for lumbar spinal stenosis (LSS) reported that surgery is superior to nonsurgical treatments, but intensive and adequate volume of physical therapy were rarely performed. The purpose of this study was to compare the 1-year follow-up outcomes of patients with LSS treated with supervised physical therapy or surgery using propensity score-matched analysis.
Methods: A total of 224 patients with LSS who received supervised physical therapy (n = 38) or surgery (n = 186) were included, of which 66 were matched on baseline demographics, radiological findings, and patient-reported outcomes.
Article Synopsis
- The study aimed to evaluate complications and mortality rates among elderly patients with cervical spine injuries in a rural Japanese hospital from January 2011 to March 2018.
- Researchers analyzed data from 398 patients, separating them into two age groups: those aged 65 and older (group Y) and those over 65 (group E). Key parameters assessed included mortality, length of hospital stay, types of cervical spine injuries, complications, and neurological deficits.
- The findings revealed that there were no significant differences in mortality or complications between the two age groups, although there was an increased tendency for C3 injuries in the older group, highlighting the need for careful monitoring in this population.
Introduction: Osteoporotic vertebral compression fracture (OVCF) in the elderly is a major public health concern. This retrospective case-control study aimed to determine the difference in interobserver reliability between radiography, magnetic resonance imaging (MRI), and computed tomography (CT), respectively, and whether CT radiological findings can predict prolonged back pain at 2 weeks after OVCFs.
Methods: Patients were divided into the prolonged back pain group or the recovered back pain group depending on the numerical rating scale at 2 weeks after admission.
Study Design: This study was a retrospective subgroup analysis of prospective cohort data.
Objective: The main objectives of this study were to develop a classification of degenerative spondylolisthesis (DS) and concurrent lumbar spinal stenosis (LSS) based on pathologic stage, and to determine how these subtypes of DS affect outcomes for minimally invasive (MIS) decompression SUMMARY OF BACKGROUND DATA:: DS with LSS is a common clinical scenario, yet there is no consensus on optimal treatment. Natural history of DS is described as early degenerative damage, followed by instability, and eventual restabilization via spondylotic changes.
Objective: Osteoporotic vertebral body fractures (OVFs) represent a significant medical and socioeconomic burden. There is ongoing debate concerning the role of cement augmentation versus conservative management, but we are increasingly recognizing the longer-term effects of kyphotic vertebral alignment on functional outcomes, pain, and subsequent fracture rates. The purpose of this study was to determine the effect of timing of intervention with percutaneous balloon kyphoplasty (BKP) for OVF on clinical and radiographic outcomes.
View Article and Find Full Text PDFPurpose: Noncontiguous double-level unstable spinal injuries (NDUSI) are uncommon and have not been well described. In this study, we aimed to better understand the patterns of NDUSI, in order to recommend proper diagnostic and treatment methods, as well as to raise awareness among traumatologists about the possibility of these uncommon injuries.
Methods: A total of 710 consecutive patients with spine fractures were treated for >9 years since 2007 at a single regional trauma center.
Background: The natural history and risk factors for lumbar degenerative spondylolisthesis (DS) remain unclear. Because it is important for physicians to take these factors into account to ensure accurate decisions regarding surgical methods, this study aimed to elucidate the natural course and risk factors for the progression of DS.
Methods: This is a prospective observation and case control study of 15-year follow-up in a rural mountainous cohort in Wakayama, Japan.
Background: To date, there has been no adequate biomechanical model that would allow a quantitative comparison in terms of stability/stiffness between a corpectomy with the posterior column preserved and a total spondylectomy with the posterior column sacrificed. The objective of this study was to perform a biomechanical comparison of 360° stabilizations for corpectomy and total spondylectomy, using the human thoracolumbar spine.
Methods: Five human cadaveric thoracolumbar spines (T8-L2) were tested according to the following loading protocol: axial compression, flexion, extension, lateral bending to the right and left, and axial rotation to the right and left.
Article Synopsis
- A population-based study called ROAD assessed the prevalence of diffuse idiopathic skeletal hyperostosis (DISH) and its connections with lumbar spondylosis (LS) and knee osteoarthritis (KOA) among 1,690 participants between 2005 and 2007.
- The study found that DISH prevalence was 10.8%, significantly higher in older individuals, particularly affecting the thoracic spine.
- Logistic regression indicated that older age, male sex, higher body mass index, and presence of LS and severe KOA were strongly associated with the occurrence of DISH, after accounting for lifestyle factors like smoking and drinking.
Article Synopsis
- - The study aims to find out which dietary nutrients might be linked to joint space narrowing (JSN) and osteophytosis in the knees of participants from the ROAD study.
- - Analyzing 827 participants, it was found that while men showed no links, women’s intake of vitamins K, B1, B2, B6, and C was significantly associated with joint health measures after adjusting for factors like age and BMI.
- - The results suggest that low intake of specific vitamins may protect against knee osteoarthritis in women, indicating potential avenues for treatment.
Article Synopsis
- The bone morphogenetic protein (BMP) pathway is crucial for the development and repair of the skeletal system, but using BMPs in clinical settings requires much higher doses in primates than in lab studies.
- A protein called LMP-1 enhances BMP signaling by preventing the degradation of Smad proteins, which are important for BMP activity.
- The study reveals that LMP-1 interacts with Jab1, a protein that usually targets Smad4 for degradation; this interaction helps maintain higher levels of osteogenic Smads in cells, promoting bone formation.
Study Design: A prospective study of de novo degenerative lumbar scoliosis in a community-based cohort.
Objectives: To investigate risk factors and natural history of de novo scoliosis in the elderly.
Summary Of Background Data: Most previous studies have focused on the risk of progression with greater curve magnitude, which often manifests with serious clinical symptoms.
Design: This study is a radiographic analysis.
Objective: To compare the fusion rates after anterior cervical discectomy and fusion (ACDF) using x-rays versus computerized tomography (CT).
Background: Although fusion status may be obvious when evaluating ACDFs performed in the remote past, determining the presence of a solid fusion at earlier time points after ACDF is often ambiguous but a necessary part of practice.
Study Design: A biomechanical study.
Objective: How much of the facet joint and the pars interarticularis (PI) can be removed in microendoscopic lateral decompression (MELD) for lumbar foraminal stenosis (LFS)?
Summary Of Background Data: MELD is a surgical modality for patients with LFS. In severe degenerative cases, unilateral facet joint resection or unilateral removal of the lateral part of the PI are sometimes needed to decompress the nerve root adequately.
OBJECTIVE: The objective of the present study is to identify dietary nutrients associated with joint space narrowing (JSN) and osteophytosis at the knee in a population-based cohort of the Research on Osteoarthritis/osteoporosis Against Disability (ROAD) study. METHODS: From the baseline survey of the ROAD study, 827 participants (305 men and 522 women) in a rural cohort were analyzed. Dietary nutrient intakes for the last month were assessed by a self-administered brief diet history questionnaire.
View Article and Find Full Text PDFBackground: The diagnosis of lumbar intraforaminal and extraforaminal stenosis (lumbar foraminal stenosis) is sometimes difficult. However, sensory nerve action potential (SNAP) decreases in amplitude when the lesion is at or distal to the dorsal root ganglion. Therefore, the amplitude of SNAP with lumbar foraminal stenosis should be decreased.
View Article and Find Full Text PDFBackground: Little information is available on the prevalence, incidence, and risk factors associated with curve progression in de-novo degenerative lumbar scoliosis (DNDLS) in the general population. Development of treatment guidelines requires further knowledge about the etiology and natural history of DNDLS in the elderly.
Methods: To identify the cumulative incidence and radiographic features of DNDLS in the elderly, the authors reanalyzed the results of lumbar radiographic examinations from the Miyama study, which was originally conducted in a Japanese rural community to determine the prevalence of vertebral fractures in Japanese people.
Objective: To clarify the individual associations of joint space narrowing (JSN) and osteophytosis at the knee with quality of life (QOL) in Japanese men and women using a large-scale population-based cohort from the Research on Osteoarthritis Against Disability (ROAD) study.
Methods: The associations of minimum joint space width (JSW) and osteophyte area in the medial compartment of the knee with QOL parameters, such as the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), were examined. Minimum JSW and osteophyte area in the medial compartment of the knee were measured using a computer-aided system for the diagnosis of knee osteoarthritis.
Article Synopsis
- The study aimed to investigate the prevalence of falls in different sex and age groups in Japan, particularly focusing on how bone and joint diseases relate to falls.
- Researchers analyzed data from 587 men and 1,088 women aged around 65 years, finding that 13.5% of men and 19.0% of women experienced falls in the past year.
- They discovered that while men had fewer factors linked to falls, women had significant associations between lower back pain, knee pain, and multiple falls, suggesting a need for further attention on these issues.
Article Synopsis
- The study conducted cross-sectional surveys to assess the health-related quality of life (QOL) in men with low back pain and knee pain, focusing on a population-based cohort.
- It aimed to determine how much these pains, along with conditions like vertebral fracture and knee osteoarthritis, affect the quality of life among older men.
- Findings revealed that low back pain significantly decreases QOL more than knee pain, particularly when combined with vertebral fractures.
Article Synopsis
- The study examined how knee and low back pain affect the quality of life (QOL) in Japanese women, utilizing various health assessment tools to gather data from 1,369 women aged over 40 from a larger cohort of 3,040 participants.
- Findings indicated that both knee pain and low back pain led to significantly lower QOL scores, with knee osteoarthritis (KL grade = 4) impacting QOL the most for women with knee pain.
- Interestingly, for low back pain, no major link was found between the KL grade and QOL loss, but a moderate association was noted between QOL loss and the presence of vertebral fractures (VFx).