Publications by authors named "Yoshinori Tsukahara"

Article Synopsis
  • The study aimed to assess the performance of a specific mixture (n-butyl cyanoacrylate-Lipiodol-iopamidol) in embolizing medium-sized arteries using various scenarios, including the use of microcoils and flow control.
  • An experimental model of the common hepatic artery was tested under six different embolization scenarios, observing the migration of the mixture after injection.
  • Results showed that the mixture effectively embolized the arteries when combined with microcoils, especially with flow control, but without flow control, it led to partial migration of the mixture away from the target site.
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  • Primary racemose hemangioma of the bronchial artery (RHBA) is a rare congenital condition involving enlarged bronchial arteries that may form abnormal connections with other blood vessels.
  • A case study reports successful balloon-assisted embolization for a 57-year-old asymptomatic woman with RHBA, utilizing a specialized catheter system to precisely deliver a treatment mixture to the affected areas.
  • This method is preferred to prevent the risk of artery rupture caused by the dilated vessels, effectively guiding treatment while controlling blood flow.
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  • Hip fractures often lead to osteoporosis-related risks and are treated with anti-osteoporotic drugs; however, the impact of strong drugs like denosumab on fracture healing is not well studied.
  • This prospective study compared early administration of denosumab with ibandronate in patients post-surgery for intertrochanteric femoral fractures to evaluate healing outcomes.
  • Results indicated no significant differences in pain levels or healing rates between the two groups, suggesting that denosumab does not delay fracture healing compared to ibandronate.
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  • The study aimed to assess a modified CT scan protocol using a lower contrast agent dose to improve the diagnosis of systemic artery-to-pulmonary artery shunts (SPSs).
  • Twenty-five patients underwent chest CT scans and conventional angiography, with two trained radiologists evaluating the effectiveness of three different CT image sets.
  • Results showed that the modified CT scan (CTA-PS) had better sensitivity and accuracy for detecting SPSs compared to the standard protocols, suggesting it could serve as a reliable alternative to traditional angiography for patients suspected of having these shunts.
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  • - The study investigates the correlation between re-ossification after palliative radiotherapy for spinal bone metastases and the preservation of vertebral body height in patients with osteolytic changes.
  • - Conducted as a retrospective observational study, it analyzed 111 vertebral bodies from 54 patients who underwent treatment between 2016 and 2020, using CT images to assess re-ossification and changes in vertebral height.
  • - Results showed that 62.2% of the vertebral bodies exhibited re-ossification, typically confirmed by CT about two months post-radiotherapy, with identified factors influencing vertebral height reduction noted before treatment.
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Purpose: This study compares the usefulness of expiratory arterial phase (EAP)-contrast-enhanced computed tomography (CT) (CECT) with that of inspiratory arterial phase (IAP)-CECT in adrenal venous sampling (AVS).

Methods: Sixty-four patients who underwent AVS and CECT at the authors' hospital between April 2013 and June 2019 were included in this study. The patients were classified into the following two groups: EAP (32 patients) and IAP (32 patients) groups.

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Article Synopsis
  • * The new mixture (N-butyl cyanoacrylate-Lipiodol-Iopamidol) is less sticky and can form larger droplets compared to the previous mixture.
  • * A case study of a 63-year-old man with a ruptured splenic artery aneurysm showed successful treatment using this advanced mixture during an emergency procedure, highlighting its efficacy for aneurysm embolization.
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A 51-year-old male patient with alcoholic cirrhosis visited our hospital for a scheduled gastrostomy replacement. During the gastrostomy replacement, he suddenly experienced a massive hemorrhage from the fistula site. Based on enhanced computed tomography findings, we concluded that collateral blood vessels from the left gastroepiploic vein had flowed into the varices near the gastrostomy as the main origin of the bleeding.

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  • * A unique case of SAP rupture was linked to a large gastric ulcer caused by infection and the use of NSAIDs, highlighting the importance of understanding different risk factors.
  • * Clinicians must recognize the specific enhanced CT images associated with SAP, be aware of potential complications like splenic infarction, and know about treatment options like arterial embolization for effective management.
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  • A study was conducted to compare the effectiveness of two treatment methods for hepatocellular carcinoma (HCC): drug-eluting bead transarterial chemoembolization (DEB-TACE) and conventional transarterial chemoembolization (cTACE), both using the drug epirubicin.
  • The trial included 200 patients with unresectable HCC, finding that cTACE had significantly higher complete response (CR) rates at both 1 and 3 months compared to DEB-TACE.
  • Despite cTACE showing higher efficacy, it also resulted in a greater incidence of adverse events than DEB-TACE, including symptoms like fatigue and increased liver enzyme levels.
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  • The study evaluated the safety and effectiveness of preoperative arterial embolization for organized hematomas in the maxillary sinus, involving seven patients who underwent this procedure prior to endoscopic sinus surgery.
  • The results showed no complications from embolization, with a median surgical blood loss of 30 mL and surgery time of 112 minutes, indicating a significant reduction in blood loss compared to non-embolization cases.
  • The findings suggest that preoperative embolization is a safe and efficient approach to minimize serious bleeding during surgery for organized hematomas of the maxillary sinus.
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Purpose: This study evaluated major vascular injury risk in distal femoral osteotomy (DFO) via the subvastus approach and examined the relationship between the posterior border of the vastus medialis (VM) and the superficial femoral artery (SFA) and vein (SFV).

Methods: Eighty limbs from 80 patients were evaluated using lower extremity computed tomographic venography. The positional relationship between the VM, SFA, and SFV was evaluated by measuring the angle between each structure and the horizontal reference point (VMA: VM angle, FAA (femoral arterial angle), FVA (femoral venous angle) and the distance between VM and the SFA and SFV (VMAD: VM-arterial distance, VMVD: VM-venous distance) in each axial slice (0/10/20/30/40 mm) proximal to the level of the superior patellar margin.

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  • Cardiospondylocarpofacial syndrome (CSCF) is a rare genetic disorder marked by growth issues, heart valve problems, bone fusions, and joint hypermobility, caused by mutations in the MAP3K7 gene.
  • The first Asian male with CSCF was identified with a novel mutation, and his case revealed additional features similar to Ehlers-Danlos syndrome and Noonan syndrome.
  • This study not only provides insights into the clinical manifestations of CSCF but also successfully documented carpal fusion through radiography, potentially broadening the understanding of its phenotypic variations.*
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  • * A new case of EWS was identified in a Japanese man, showcasing additional symptoms including spinal issues and the presence of perineural cysts, which had not been previously noted in EWS patients.
  • * This observation may broaden the understanding of EWS and how mutations in cadherin 11 can affect skeletal and neurological development, highlighting the need for further research into these findings.
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  • * Out of 39 HCC cases, 59% showed a PTHR, which correlated with significantly higher iron deposition in both the peritumoral area and the surrounding liver tissue, compared to cases without PTHR.
  • * The findings suggest that the presence of a PTHR is linked to increased peritumoral and background liver iron levels, but not to the fibrous capsule surrounding the tumor.
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Purpose: To compare the visualization of hemodynamic imaging findings of hypervascular hepatocellular carcinoma (HCC) on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) using radial volumetric imaging breath-hold examination with k-space-weighted image contrast reconstruction (r-VIBE-KWIC) versus dynamic computed tomography during hepatic arteriography (dyn-CTHA).

Materials And Methods: We retrospectively reviewed the databases of preoperative DCE-MRI using r-VIBE-KWIC, dyn-CTHA, and postoperative pathology of resected specimens. Fourteen patients with 14 hypervascular HCCs underwent both DCE-MRI and dyn-CTHA.

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  • The study aimed to compare the time-intensity curves (TICs) of the abdominal aorta during dynamic contrast-enhanced MRI (DCE-MRI) using two different contrast agents: Gd-DTPA and Gd-EOB-DTPA.
  • Ten healthy volunteers participated, with variations in injection rates and contrast agents, and signal intensities were analyzed to determine the contrast enhancement ratio (CER) and the time-to-peak.
  • Results indicated distinct TIC patterns between contrast agents, showing a double peak in Gd-DTPA and a single peak in Gd-EOB-DTPA, with significant differences in maximum CER and time-to-peak, suggesting an optimized approach for DCE-MRI protocols may benefit
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  • A 58-year-old woman undergoing treatment for chronic hepatitis C developed interstitial pneumonia during her therapy with pegylated interferon (PEG IFN)-α-2a and ribavirin (RBV).
  • Serum levels of KL-6, a marker for lung disease activity, increased significantly during the treatment, indicating a potential problem.
  • The patient recovered after stopping the therapy, suggesting that regular monitoring of KL-6 levels could help prevent the progression of interstitial pneumonia related to this treatment.
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