Publications by authors named "Yoshinori Omori"
Article Synopsis
- Subependymal giant cell astrocytoma (SEGA) occurs in 5-20% of patients with tuberous sclerosis complex (TSC) and can lead to complications like hydrocephalus.
- A 14-year-old boy with TSC developed SEGA and hydrocephalus, with treatments reducing tumor size but not resolving ventricular enlargement.
- The situation emphasizes the importance of considering multiple factors affecting cerebrospinal fluid (CSF) dynamics, and highlights the need for improved treatment strategies in TSC patients with SEGA.
Article Synopsis
- Spinal lipomas are congenital defects that grow like normal fat tissue after birth, prompting a study to track their size changes in relation to body mass index (BMI).
- The research included 27 patients, analyzing MRI results at two points before surgery, focusing on age-related growth patterns of the lipomas and surrounding tissues.
- Findings revealed that younger patients (under 3 months) experienced significantly higher growth rates in spinal lipomas compared to the normal spinal canal, indicating potential complications such as obstruction or distortion of the spinal cord.
Article Synopsis
- The study aims to differentiate between physiological midline defects of the lumbosacral vertebral arches and pathological spina bifida using CT imaging.
- Analyzed data from 115 patients revealed a high rate (66.1%) of physiological defects, particularly in those under 6 years old, with a mean of 1.6 defective arches per patient.
- The most common defect locations were near the sacral hiatus (S3) and S1, with the findings helping to improve the diagnostic process for clinicians.
The systemic injection of human mesenchymal stem cells (hMSCs) prepared from adult bone marrow has therapeutic benefits after cerebral artery occlusion in rats, and may have multiple therapeutic effects at various sites and times within the lesion as the cells respond to a particular pathological microenvironment. However, the comparative therapeutic benefits of multiple injections of hMSCs at different time points after cerebral artery occlusion in rats remain unclear. In this study, we induced middle cerebral artery occlusion (MCAO) in rats using intra-luminal vascular occlusion, and infused hMSCs intravenously at a single 6 h time point (low and high cell doses) and various multiple time points after MCAO.
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