Publications by authors named "Yoshinobu Kure"
Front Cell Dev Biol
November 2023
Article Synopsis
- Elevated levels of angiotensin II (AngII) cause cardiomyocyte hypertrophy, which is linked to cardiovascular diseases, and current treatments are not very effective at reversing this issue.
- A study investigates the Japanese Kampo medicine Moku-boi-to (MBT) for its potential to protect against AngII-induced cardiomyocyte hypertrophy and cell death, finding that it improves calcium signaling, reduces reactive oxygen species (ROS), and enhances mitochondrial function.
- Results suggest that MBT has cardioprotective effects through mechanisms potentially involving the angiotensin receptor, highlighting its promise as a safe and effective treatment for cardiac hypertrophy.
