Creation, effects on embryo quality, and clinical outcomes of a new embryo culture medium with 31 optimized components derived from human oviduct fluid: A prospective multicenter randomized trial.

Purpose: Our aim is to make an ideal embryo culture medium close to human oviduct fluid (HOF) components, and to evaluate the quality of this medium with embryo quality and clinical outcomes in assisted reproductive technology (ART) by a prospective randomized controlled trial (RCT).

Methods: Study I: HOF was collected laparoscopically from patients (= 28) with normal pelvic findings. According to HOF analysis results, the new medium "HiGROW OVIT" (OVIT) was designed.

In vitro fertilization embryo development from caffeine-treated murine sperm.

Purpose: To evaluate the effect of long-term caffeine administration on murine sperm and subsequent in vitro fertilization (IVF).

Methods: Male mice were injected with various doses (0, 0.2 and 1.

Effect of long-term caffeine administration to mice on in vitro fertilization and embryo development using oocytes.

Purpose: To evaluate the effect of long-term caffeine administration to mice on in vitro fertilization (IVF) of oocytes.

Methods: Mice were injected with different dosages (0, 0.1, and 1.

Relationship between follicular fluid hormone levels, embryo quality, and maternal age during fertilization after the short or long protocol with a gonadotropin releasing hormone agonist.

To examine the relationship between embryo quality and follicular fluid hormonal level in short and long protocol gonadotrophin releasing hormone agonist treatment cycles. A total of 90 patients had non-polycystic ovary syndrome (non-PCOS) and 10 had PCOS. A total of 100 subjects underwent fertilization (IVF).

Enhancing the fertility of poor responders by treatment with estrogen rebound combined with a short protocol.

To assess the efficacy of estrogen rebound (ER) plus flare-up by gonadotropin releasing hormone agonist (GnRH-a) in poor responders who failed to become pregnant prior to a long protocol treatment. The patients comprised of thirty-one infertile patients with oocyte retrieval levels of less than five, who had undergone several long protocol treatment cycles. The efficacy of treatment with the ER plus flare-up from GnRH-a was compared with the prior long protocol treatment.