Microbiol Resour Announc
January 2025
In this study, a draft genome sequence of kiy1 isolated from unpasteurized honey in Japan was analyzed. This strain was reported to be a promising arabitol-producing strain, and this report contributes to a better understanding of arabitol production in yeasts.
View Article and Find Full Text PDFIntroduction: Patients with type 2 diabetes (T2D) undergoing dialysis exhibit a higher mortality rate compared with those with other conditions, primarily due to vascular complications including coronary artery disease, heart failure and stroke. Sodium-glucose cotransporter 2 (SGLT2) inhibitors, a type of drug for T2D, have reportedly decreased cardiovascular and renal events in patients with heart failure and chronic kidney disease, irrespective of diabetes presence. Nevertheless, the evidence supporting the use of SGLT2 inhibitors in patients undergoing dialysis has been limited.
View Article and Find Full Text PDFBiosci Biotechnol Biochem
August 2024
d-Arabitol, an alternative sweetener to sugar, has low calorie content, high sweetness, low glycemic index, and insulin resistance-improving ability. In this study, d-arabitol-producing yeast strains were isolated from various commercial types of miso, and strain Gz-5 was selected among these strains. Phylogenetic tree analysis of the internal transcribed spacer sequence revealed that strain Gz-5 was distinct from Zygosaccharomyces rouxii, a major fermenting yeast of miso.
View Article and Find Full Text PDFArabitol is gaining attention in the food industry as an alternative sweetener owing to its low-caloric and non-cariogenic characteristics. The yeast strain kiy1 was newly isolated from unpasteurized honey for arabitol production. Based on internal transcribed spacer sequence analysis, the isolated strain was identified as Zygosaccharomyces siamensis.
View Article and Find Full Text PDFMeasurement-based quantum computation with optical time-domain multiplexing is a promising method to realize a quantum computer from the viewpoint of scalability. Fault tolerance and universality are also realizable by preparing appropriate resource quantum states and electro-optical feedforward that is altered based on measurement results. While linear feedforward has been realized and become a common experimental technique, nonlinear feedforward was unrealized until now.
View Article and Find Full Text PDFBackground: Zalaria sp. Him3 was reported as a novel fructooligosaccharides (FOS) producing yeast. However, Zalaria spp.
View Article and Find Full Text PDFControlling the temporal waveform of light is the key to a versatile light source in classical and quantum electronics. Although pulse shaping of classical light is mature and has been used in various fields, more advanced applications would be realized by a light source that generates arbitrary quantum light with arbitrary temporal waveforms. We call such a device a quantum arbitrary waveform generator (Q-AWG).
View Article and Find Full Text PDFTelecommunication wavelength with well-developed optical communication technologies and low losses in the waveguide are advantageous for quantum applications. However, an experimental generation of non-classical states called non-Gaussian states at the telecommunication wavelength is still underdeveloped. Here, we generate highly-pure-single-photon states, one of the most primitive non-Gaussian states, by using a heralding scheme with an optical parametric oscillator and a superconducting nano-strip photon detector.
View Article and Find Full Text PDFPurpose: Anatomic isolated liver segmentectomy 8 (ILSeg8) for malignancies remains technically challenging. The feasibility, safety, and oncologic validity of laparoscopic ILSeg8 are undefined, and thus were evaluated in comparison with the open approach.
Methods: This study enrolled 35 open and 29 laparoscopic ILSeg8 cases of hepatocellular carcinoma (n = 47), metastatic liver tumors (n = 16), and intrahepatic cholangiocarcinoma (n = 1) at our institution.
Continuous-wave (CW) squeezed light is used in the generation of various optical quantum states, and thus is a fundamental resource of fault-tolerant universal quantum computation using optical continuous variables. To realize a practical quantum computer, a waveguide optical parametric amplifier (OPA) is an attractive CW squeezed light source in terms of its THz-order bandwidth and suitability for modularization. The usages of a waveguide OPA in quantum applications thus far, however, are limited due to the difficulty of the generation of the squeezed light with a high purity.
View Article and Find Full Text PDFBackground: Autoimmune tubulointerstitial nephritis (TIN) is characterized by immune-mediated tubular injury and requires immunosuppressive therapy. However, diagnosing TIN and assessing therapeutic response are challenging for clinicians due to the lack of useful biomarkers. Pathologically, CD4 T cells infiltrate to renal tubulointerstitium, and soluble interleukin-2 receptor (sIL-2R) has been widely known as a serological marker of activated T cell.
View Article and Find Full Text PDFPreviously, we found that a multicopper oxidase (IOX) produced by Iodidimonas sp. Q-1, an iodide (I)-oxidizing marine bacterium, exhibited significant decolorization activity toward various anionic dyes. In this study, the potential capacity of IOX for decolorization of cationic dyes such as malachite green (MG), crystal violet (CV), and methylene blue (MB) was determined.
View Article and Find Full Text PDFBackground: Chronic high Epstein-Barr virus loads (CHEBV) are commonly observed in pediatric liver transplant patients. However, it is unclear how CHEBV impacts the liver graft. The aim of this study was to clarify the clinical and pathological impacts of CHEBV on the liver graft.
View Article and Find Full Text PDFAims: This study aimed at obtaining a novel fructooligosaccharides (FOS)-producing yeast, which was different from conventional FOS producers, Aureobasidium spp.
Methods And Results: Strain Him3 was newly isolated from a Japanese dried sweet potato as a FOS producer. The strain exhibited yeast-like cells and melanization on the potato dextrose agar medium, and formed very weak pseudomycelia on the yeast extract polypeptone dextrose agar medium.
Background: Minimally invasive pancreaticoduodenectomy (MIPD), including laparoscopic pancreaticoduodenectomy (LPD) and robotic pancreaticoduodenectomy (RPD), is technically demanding because of pancreaticojejunostomy (PJ). Postoperative pancreatic fistula (POPF) is the most serious complication of MIPD and open pancreaticoduodenectomy (OPD). Contrary to expectations, conventional PJ in MIPD did not improve POPF rate and length of hospital stay.
View Article and Find Full Text PDFTumor lysis syndrome (TLS) is an oncologic emergency caused by release of intracellular tumor components due to massive tumor lysis and is rare in patients with hepatocellular carcinoma (HCC). We describe a case of TLS with rupture of HCC induced by lenvatinib in a patient with advanced HCC. A 72-year-old man who presented with right upper abdominal pain was diagnosed as having advanced HCC with a high tumor burden by contrast-enhanced computed tomography and percutaneous hepatic tumor biopsy.
View Article and Find Full Text PDFBackground: In an increasing number of patients undergoing radical surgery for perihilar cholangiocarcinoma [1-3], the intrahepatic bile duct is conventionally transected after the vessels to be preserved or reconstructed are confirmed [3,4]. In patients with extremely advanced perihilar cholangiocarcinoma having massive vascular involvement, it is sometimes difficult to confirm the vessels for reconstruction because of restricted working space and/or anatomical variants, even after liver parenchymal dissection [4]. When the vessels cannot be confirmed, the tumor is usually unresectable [4].
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