Publications by authors named "Yoshihito Kubo"
Article Synopsis
- - This study investigates how basal cell hyperplasia contributes to the development of eosinophilic chronic rhinosinusitis (eCRS), particularly in the nasal polyp epithelium.
- - Researchers cultured normal human bronchial epithelial cells to create two different cell types: Basal-like cells (cBC) and Epithelial cells (cEC), comparing their characteristics through various scientific methods.
- - The findings reveal that type 2 cytokines like IL-4 and IL-13 promote the growth of basal cells, which in turn produce inflammatory markers that worsen the condition in nasal polyps associated with eCRS.
Epidemiological studies suggest that poor nutrition during pregnancy influences offspring predisposition to experience developmental and psychiatric disorders. Animal studies have shown that maternal undernutrition leads to behavioral impairment, which is linked to alterations in monoaminergic systems and inflammation in the brain. In this study, we focused on the ethanolamine plasmalogen of the brain as a possible contributor to behavioral disturbances observed in offspring exposed to maternal undernutrition.
View Article and Find Full Text PDF