Publications by authors named "Yoshihiro Mihara"

Shirasu balloon (SB) is a hollow glassy sphere produced from volcanic deposits by heating that can float up on water owing to its hollow structure. In this study, a novel adsorbent for the removal of cesium ion in water was developed by the modification of the surface of the SBs with magnetite (Mag) and Prussian blue (PB). The developed adsorbent (PB-Mag-SB) was characterized by elemental analysis, X-ray diffraction, and Fourier transform infrared spectrometry and the magnetism of the adsorbent.

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We examined the chemical constitution of the red alga Laurencia saitoi Perestenko, collected from Katsuura, Boso Peninsula, Chiba Prefecture, Japan. This specimen produced a new polyhalogenated acetogenin, named katsuurallene (1), which structure was determined by the spectral methods, along with known diterpene, deoxyparguerol (2) and triterpene, thyrsiferol (3). In this paper we describe the structural elucidation of katsuurallene together with some biological activities.

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To identify the CYP isoforms involved in the production of 2-hydroxyestradiol 17-sulfate (2-OH-ES), which we assume to be an antioxidant in vivo, the 2-hydroxylation reaction of estradiol 17-sulfate (ES) by human liver microsome was investigated. As a result, it was estimated that CYP2C8 and 2C9 were largely involved in the production of 2-OH-ES. Therefore, the 2-hydroxylation kinetic analysis of ES was performed for both CYPs, and the metabolic clearance V/K (µL/nmol CYP/min) was determined.

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For various pollutants with different specific gravity values, adsorbents having similar specific gravity values as those of target pollutants are necessary to achieve enough contact time. The purpose of this work is to introduce a self-vertical migration system to adsorbents for wastewater treatment. An alginate hydrogel composite with controlled specific gravity and buoyancy was successfully developed, which can first sink to the bottom of water and then float up on the surface after the adsorption.

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Microspheres of aluminosilicate glass from volcanic sediment, whose surfaces were modified with functional groups, Shirasu-balloons (SB), were investigated as an adsorbent to remove cadmium ions from contaminated soil. The introduction of thiol groups (-SH) on the surface of SB enabled it to adsorb cadmium ions. Meanwhile, the introduction of an alkyl group (-ODS) made the surface of SB hydrophobic, and consequently increased the mechanical strength of SB.

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Background/aim: Mulberry (Morus alba L.) leaves (ML) contain many functional components, such as 1-deoxynojirimycin, flavonoids (rutin, quercetin, kaempferol). It is well known that 1-deoxynojirimycin functions to suppress increases in blood glucose level by α-glucosidase inhibitory activity.

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A carbohydrate/electro-transfer peptide probe was fabricated to perform cell sensing. The probe consisted of a cello-oligosaccharide that was created by the conjugation of an electron-transfer peptide (YC) and a carbohydrate via a Schiff base. An oxidation wave due to a phenolic hydroxyl group was obtained by scanning with a glassy carbon electrode.

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Background/aim: Oligonol® (OLG) is a low-molecular-weight lychee fruit polyphenol mainly containing catechin-type monomers and oligomers of proanthocyanidins. Dietary OLG supplementation reportedly improves lipid metabolism disorder and lowers the visceral fat level in animal and human studies. Thus, we investigated the mechanism behind the protective and beneficial effects of OLG on a Western diet (WD)-induced metabolic syndrome (MetS) of a murine model.

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Background: Perilla (Perilla frutescens Britton) leaf comprises many types of active components, mainly flavonoids, and acts as an anti-inflammatory agent in in vitro and in vivo atopic dermatitis (AD) models.

Objective: We investigated the effects of orally administered perilla leaf extract (PLE) on the symptoms of AD induced by Dermatophagoides farinae extract (DFE) in NC/Nga AD model mice.

Methods: The mice were allowed free intake of 0.

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A low cost and environmentally friendly adsorbent was developed based on leaf of platanus sp. to adsorb cadmium ion in water. The adsorbent was modified with citric acid and then also encapsulated in agar for easy separation after the adsorption process.

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The present study investigated the adsorptive ability of carbon materials (C1 and C2) released during the combustion of woody biomass. The physical and chemical properties, adsorption dynamics and adsorption isotherms of the adsorbents were compared with those of commercially available carbon that was powdered and activated. The percent nitrobenzene adsorption from an aqueous solution (nitrobenzene: 50mg/L) after 3h of adsorption using C1 was 92% compared with 81% when using the activated carbon powder.

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