Publications by authors named "Yoshihide Okagami"
Article Synopsis
- The research aimed to evaluate how effective antimicrobial photodynamic therapy (aPDT) is in eliminating mycoplasmas from contaminated cells, which are common in cell cultures.
- Mycoplasmas are typically removed using antibiotics, but this can lead to antibiotic-resistant bacteria; thus, aPDT, combined with methylene blue and red LED light, was tested as a safer alternative.
- The results showed that aPDT significantly reduced live mycoplasmas in treated human embryonic kidney cells without harming them, indicating its potential as a method for cleaning contaminated cell cultures.
Aim: Light-emitting diodes have been investigated as new light activators for photodynamic therapy. We investigated the bactericidal effects of high-power, red light-emitting diodes on two periodontopathic bacteria in vitro.
Methods: A light-emitting diode (intensity: 1100 mW/cm(2) , peak wavelength: 650 nm) was used to irradiate a bacterial solution for either 10 or 20 s.
Article Synopsis
- A new Er:YAG laser light delivery system has been developed using a polymer-coated silver hollow waveguide and a quartz sealing cap, aiming to improve calculus fragmentation.
- Various sealing caps with different end shapes were tested for their ability to focus laser light in air and water, demonstrating effective transmission of high-energy laser pulses in saline solutions.
- In vitro experiments confirmed the system's efficacy in lithotripsy, with results indicating that caps designed for better focusing were more successful in breaking down calculi, and there were observations regarding the wear of the caps after use.