Publications by authors named "Yoshiaki Tsukizawa"
Article Synopsis
- The review aims to evaluate the diagnostic effectiveness of contrast-enhanced CT and MRI for detecting acute pelvic inflammatory disease (PID) in emergency care settings.
- A comprehensive search identified 2,619 studies, out of which four were eligible, involving 635 patients, but all had a high risk of bias in diagnosing PID.
- The results indicated that contrast-enhanced CT has a sensitivity of 79% and specificity of 99%, while MRI has a higher sensitivity of 95% but a lower specificity of 89%, with both imaging techniques showing uncertain reliability for accurate diagnosis.
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
View Article and Find Full Text PDFNivolumab, a new immune checkpoint inhibitor that has been found to improve outcomes for patients with some advanced cancers, is being increasingly used. Immune checkpoint inhibitors can cause immune-related adverse events, including dermatitis, enterocolitis, hepatitis and hypophysitis, but adrenal insufficiency rarely occurs. We present a case of Nivolumab-induced adrenal insufficiency in a man who complained of refractory hypotension.
View Article and Find Full Text PDFMammalian circadian clocks have a hierarchical organization, governed by the suprachiasmatic nucleus (SCN) in the hypothalamus. The brain itself contains multiple loci that maintain autonomous circadian rhythmicity, but the contribution of the non-SCN clocks to this hierarchy remains unclear. We examine circadian oscillations of clock gene expression in various brain loci and discovered that in mouse, robust, higher amplitude, relatively faster oscillations occur in the choroid plexus (CP) compared to the SCN.
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