Publications by authors named "Yoshiaki Hirohata"

Article Synopsis
  • * Researchers prepared dMBs by modifying human fibroblasts and implanted silicon tubes under the skin of mice to create biosheets, which were then seeded with dMBs and a nanogel or Matrigel.
  • * Results showed that the combination of dMBs with the nanogel led to better muscle cell development and expression, indicating potential for using these tissues for regenerative medicine.
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Article Synopsis
  • A study was conducted in Japan to assess the long-term functional outcomes for infants who had surgery for sacrococcygeal teratoma (SCT), focusing on issues like tumor recurrence and functional impairments.
  • Among 355 patients analyzed, 23.4% experienced long-term complications (such as anorectal, urinary, and lower limb dysfunction) and 11.8% had tumor recurrence, highlighting significant postoperative risks.
  • The study identified several risk factors for both dysfunction and recurrence, emphasizing the need for ongoing monitoring and the establishment of treatment guidelines for affected patients.*
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Cholangiolocellular carcinoma (CoCC) is a rare malignant liver tumor derived from hepatic progenitor cells, which exist in the canals of Hering. We encountered a case of CoCC with an extremely poor clinical course, initially showing abnormally elevated serum alfa-fetoprotein (AFP). A 72-year-old male presented with a liver tumor and abnormally elevated serum AFP levels (16,399 ng/ml).

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