Safety of Femoral Nerve Blockade for Hip Fractures inAdult Patients Treated with Anti-Xa Direct Oral Anticoagulants: A Pilot Study.

Background: Limited data exist regarding the safety of ultrasound-guided femoral nerve blockade (US-FNB) in patients with hip fractures treated with anti-Xa direct oral anticoagulants (DOAC).

Objectives: To compare the safety outcomes of US-FNB to conventional analgesia in patients with hip fractures treated with anti-Xa DOAC.

Methods: This observational exploratory prospective study included 69 patients who presented to our emergency department (ED) in 3 years with hip fracture and who were treated with apixaban or rivaroxaban.

Can enoxaparin safely replace unfractionated heparin during coronary intervention in acute coronary syndromes?

Background: Enoxaparin has gained wide acceptance in patients with acute coronary syndromes. However, there is uncertainty regarding management of patients who require coronary intervention while on enoxaparin. Some physicians withhold the morning dose of enoxaparin prior to coronary intervention while others switch patients to unfractionated heparin.