Publications by authors named "Yosanly Cornelio Puello"
Article Synopsis
- A study was conducted with 2,300 patients in the Dominican Republic between March 2021 and August 2022 to track changes in antibodies against the SARS-CoV-2 spike protein.
- The geometric mean of these spike-binding antibodies significantly increased from 6.6 BAU/mL early in the study to 1,332 BAU/mL by mid-2022.
- The results indicated that higher antibody levels were associated with a lower likelihood of acute infection, suggesting that monitoring both antibody levels and viral presence can help assess community immunity against emerging COVID-19 variants.
SARS-CoV-2 seroprevalence, cumulative infections, and immunity to symptomatic infection - A multistage national household survey and modelling study, Dominican Republic, June-October 2021.
Eric J Nilles Cecilia Then Paulino Michael de St Aubin Angela Cadavid Restrepo Helen Mayfield Yosanly Cornelio Puello
Lancet Reg Health Am
December 2022
Article Synopsis
- A study in the Dominican Republic assessed SARS-CoV-2 immunological protection and found that a significant percentage of the population had been exposed or infected.
- Out of 6,683 participants, the research estimated that 85% had immunological exposure, with 78% achieving at least 50% protection against symptomatic infection from the ancestral strain and 66% against the Delta strain.
- Factors such as age, outdoor work, smoking, urban living, and vaccination status influenced the level of protection, highlighting variations in immunological response across different demographics.