Publications by authors named "Yorihisa Moro"
Background/aim: We have previously reported that alternate-day S-1 had comparable effects and milder adverse events than the respective consecutive-day regimen in head and neck cancer (HNC) patients. The aim of this study was to investigate the anticancer effects of both regimens and underlying mechanisms in vitro.
Materials And Methods: Two head and neck squamous cell carcinoma (HNSCC) cell lines were treated with 5-FU given on an alternate-day or consecutive-day schedule.
Article Synopsis
- Sentinel node navigation surgery is being explored for oral cancer, specifically for pharyngeal and laryngeal cancers, using a combination of imaging techniques in animal studies.
- The study involved injecting a tracer mixture (indocyanine green and Sonazoid) in rabbits and swine, with successful identification of sentinel lymph nodes using infra-red cameras and ultrasound.
- Results indicated that the detection method was effective and safe, showing no adverse effects and suggesting that this technique could improve surgeries for head and neck cancers, warranting further clinical research.
Aim: This study analyzed the safety and feasibility of alternate-day S-1, a mixture of tegafur, dehydroxypyrimidine and potassium oxonate, as adjuvant chemotherapy for head and neck cancers.
Patients And Methods: Patients with head and neck squamous cell carcinoma (HNSCC) who underwent primary treatment received alternate-day S-1 (80 mg/day for 1 year). The primary end-point was treatment completion rate.
Purpose. One of the common side effects experienced by head and neck cancer patients on chemoradiotherapy is mucositis. Severe mucositis may be controllable by limiting cancer therapy, but it has resulted in decreasing the completion rate of chemoradiotherapy.
View Article and Find Full Text PDFBackground: The purpose of this study was to evaluate the efficacy of sentinel lymph node biopsy (SLNB) in early head and neck squamous cell carcinoma (HNSCC).
Methods: The PubMed database was searched for studies published before October 31, 2012. Pooled values for the sentinel lymph node identification rate, sensitivity, false-negative rate, negative predictive value, and accuracy were calculated.