Publications by authors named "Yorgun H"

Background: Atypical atrial tachycardia (AT) is a commonly encountered rhythm disorder, especially in patients with underlying atrial scar. Peak frequency (PF) annotation of bipolar electrograms is a novel method that mainly aims to discriminate near-field and far-field signals.

Objective: This study aimed to evaluate the PF annotation of low-voltage zones and deceleration zones during sinus/paced rhythm and their role in predicting the critical isthmus (CI) and termination sites of atypical ATs.

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Background: Malignant arrhythmia due to ventricular depolarization and repolarization alterations after atrioventricular node (AVN) ablation is a known clinical entity. Here, we aimed to demonstrate the ventricular depolarization and repolarization changes in patients who underwent left bundle branch area pacing (LBBaP) and AVN ablation.

Methods: This is a single-center, retrospective preliminary study (n = 10).

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Background & Objective: Successful execution of exercise-based cardiac rehabilitation programs, an important branch of physiotherapy in individuals with coronary artery disease (CAD), depends on adequate cognitive abilities. It has been identified that coronary microvascular dysfunction, marked by reduced coronary flow reserve, is associated with impaired cerebral blood flow, affecting haemodynamic and cognitive performance. This study aimed to investigate how cognitive function influences functional capacity and differences in fatigue perception in CAD patients.

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Heart rhythm management is a continuously evolving sub-speciality of cardiology. Every year, many physicians and allied professionals (APs) start and complete their training in cardiac implantable electronic devices (CIEDs) or electrophysiology (EP) across the European Heart Rhythm Association (EHRA) member countries. While this training ideally ends with an EHRA certification, the description of the learning pathway (what, how, when, and where) through an EHRA core curriculum is also a prerequisite for a successful training.

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Background: Superior vena cava (SVC) is atrial fibrillation (AF)'s most common non-pulmonary vein (PV) foci. Studies reported conflictory results when SVC isolation (SVCi) was combined with PVi and long-term outcomes were lacking. Therefore, we aimed to evaluate the long-term efficacy and safety of empirical SVCi as an adjunct to cryoballoon-based PV isolation (PVi) in persistent AF ablation.

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Atrial tachycardia (AT) is a common rhythm disorder, especially in patients with atrial structural abnormalities. Although voltage mapping can provide a general picture of structural alterations which are mainly secondary to prior ablations, surgery or pressure/volume overload, data is scarce regarding the functional characteristics of low voltage regions in the atrium to predict critical isthmus of ATs. Recently, functional substrate mapping (FSM) emerged as a potential tool to evaluate the functionality of structurally altered regions in the atrium to predict critical sites of reentry.

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Article Synopsis
  • * It analyzed 205 patients - 32 with persistent LAAT - who underwent LAAC from 2015 to 2023, documenting their health profiles and monitoring for major clinical events post-procedure.
  • * Results showed successful LAA closure in all cases, no major complications during the first month, and a promising long-term efficacy for stroke prevention among patients with persistent LAAT, indicating that LAAC is a viable option for these patients.
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Ictal asystole (IA) is a rare but potentially life-threatening complication of focal epilepsy. The sudden onset of loss of consciousness and drop attacks in a patient with chronic epilepsy should suggest the possibility of this complication. Once the diagnosis is established, rapid management should be considered, especially in high-risk cases.

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Cryoballoon-based catheter ablation has emerged as an efficacious and safe therapeutic intervention for patients with paroxysmal atrial fibrillation (PAF). PAF is primarily associated with the triggers in the pulmonary vein (PV). However, persistent atrial fibrillation (PeAF) is a complex condition that involves changes in the atrial substrate and the presence of non-PV triggers.

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Functional atrial mapping is an emerging mapping modality to predict potential critical sites with a role in the maintenance of tachycardia. We report a case of atrial late activation mapping under sinus rhythm predicting the critical isthmus of a left atrial tachycardia. Our findings demonstrate the utility of an atrial isochronal late-activation mapping approach to predict the critical isthmus of re-entry.

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Background: Atrial tachycardia (AT) is a commonly encountered rhythm disorder in patients with underlying atrial scar. The role of atrial late activation mapping during sinus rhythm to predict the critical isthmus (CI) of AT has yet to be systematically evaluated. We aimed to investigate the relationship between the functional substrate mapping (FSM) characteristics and the CI of reentrant ATs in patients with underlying atrial low-voltage areas.

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Introduction: Recent reports highlighted the role of epicardial connections in the development of biatrial tachycardia circuits.

Methods: We reported a case of 60-year-old female patient who was admitted with recurrent atrial tachycardia (AT) after endocardial pulmonary vein isolation and anterior mitral line formation.

Results: Epicardial activation map demonstrated fragmented continuous potentials at the Bachmann's bundle region with good entrainment response.

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Aims: Oesophageal fistula represents a rare but dreadful complication of atrial fibrillation catheter ablation. Data on its incidence, management, and outcome are sparse.

Methods And Results: This international multicentre registry investigates the characteristics of oesophageal fistulae after treatment of atrial fibrillation by catheter ablation.

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There is emerging data indicating that long-standing vigorous exercise may be associated with atrial structural remodelling. This remodelling process is may be the cause of the increasing frequency of atrial arrythmias in athletes. Early diagnosis of atrial remodelling by atrial imaging could have a role in management of atrial arrythmias in elite athletes.

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Background: The present study aimed to identify the frequency of Fabry disease in patients with cardiac hypertrophy of unknown etiology and to evaluate demographic and clinical characteristics, enzyme activity levels, and genetic mutations at the time of diagnosis.

Methods: This national, multicenter, cross-sectional, single-arm, observational registry study was conducted in adult patients with a clinical echocardiographic diagnosis of left ventricular hypertrophy and/or the presence of prominent papillary muscle. In both genders, genetic analysis was performed by DNA Sanger sequence analysis.

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Aims: There is an increasing trend evaluating the role of non-pulmonary vein (PV) triggers to improve ablation outcomes in persistent atrial fibrillation (AF) as pulmonary vein isolation (PVI) strategy alone has modest outcomes. We investigated the long-term safety and efficacy of left atrial appendage isolation (LAAi) in addition to PVI using cryoballoon (CB) in persistent AF.

Methods And Results: In this multicentre retrospective analysis, we included a total of 193 persistent AF patients (mean age: 60 ± 11 years, 50.

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Objective: Although the efficacy and safety of left atrial (LA) appendage (LAA) closure in patients with atrial fibrillation (AF) have been well documented in randomized controlled trials and real-world experience, there are limited data in the literature about the impact of LAA closure on diastolic functions. The study aimed to examine the impact of LAA closure on diastolic function and natriuretic peptide levels in patients with AF.

Patients And Methods: Twelve non-valvular AF patients with high risk for developing cardioembolic stroke and contraindications to warfarin underwent LAA occlusion with the WATCHMAN device (Atritech Inc.

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Article Synopsis
  • The study aimed to compare the safety and effectiveness of cryoballoon (CB) and radiofrequency (RF) ablation techniques in patients with atrial fibrillation (AF) who also have a left common pulmonary vein (LCPV).
  • A total of 127 patients were analyzed, with no significant differences found in procedure success rates (97.5% for CB vs. 97.9% for RF) or complication rates (7.5% for CB vs. 8.5% for RF).
  • During an average follow-up period of about 20 months, recurrence rates of atrial tachyarrhythmias were similar for both techniques (35.0% for
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Background: The presence of atrial fibrosis has already been known as a risk factor for atrial fibrillation (AF) development. We aimed to evaluate atrial fibrosis with previously defined three different methods, which were cardiac magnetic resonance imaging (C-MRI), echocardiographic strain imaging, and biomarkers and show the relationship between these methods in patients with AF scheduled for cryoballoon ablation.

Methods: A total of 30 patients were enrolled.

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The common ostium of left and right inferior PVs is an extremely rare variant which was only reported in 16 cases undergoing catheter ablation. Thus, electrophysiologists should be careful about such an exremely rare PV variants for the safety and efficacy of ablation. Pre-procedural CTA is a valuable tool to decide on the ablation strategy in patients with such a very rare PV anomaly.

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Objective: The systematic coronary risk evaluation (SCORE) estimates the 10-year risk of fatal cardiovascular disease (CVD), and its application is recommended. The absolute risk of CVD, independent of risk factors, is relatively low in young individuals. Expressing the risk as their "risk age" may aid in understanding the risk.

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Article Synopsis
  • A study compared the efficacy and safety of two types of mechanical dilator sheaths, TightRail™ and Evolution, in transvenous lead extraction (TLE) procedures over a span of nine years, involving 566 lead extractions across 302 patients.
  • Results showed no significant differences in procedural success rates, clinical success, and major complications between the two groups, indicating that both devices can effectively and safely remove leads.
  • Factors such as lead dwell time, the number of extracted leads, and baseline leukocyte count were found to influence procedural success, while chronic renal disease, heart failure, and coagulopathy were linked to all-cause mortality.
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