Publications by authors named "Yoosefi M"
Article Synopsis
- Alcohol has been banned in Iran for over 40 years, leading to underreported consumption; a study surveyed 27,874 adults to assess actual alcohol use and its contributing factors.
- The study found a lifetime alcohol consumption prevalence of 6.9%, with significant differences between men (13.7%) and women (1.4%); the average per capita consumption was 0.12 liters.
- Factors like being a smoker, younger age, higher wealth, and education levels correlated with increased alcohol consumption, as well as links to health issues like heart attacks and physical injuries, prompting the need for targeted preventive measures.
Article Synopsis
- The study investigates the prevalence and cardiovascular disease (CVD) risk of metabolically healthy obesity (MHO) in Iranian adults, finding that about 6.42% are classified as MHO.
- Nearly 25% of obese individuals, with a higher prevalence among men and women, showed MHO characteristics, and this group was younger than those with metabolically unhealthy obesity (MUO).
- Although MHO has a lower CVD risk compared to MUO, there is a possibility that individuals with MHO may transition to a less healthy state over time.
Article Synopsis
- In patients with cystic fibrosis treated with elexacaftor/tezacaftor/ivacaftor (ETI), significant improvements in sinonasal symptoms and a notable increase in nasal nitric oxide (nNO) levels were observed after several months of treatment.
- The study involved measuring nNO levels in 25 PwCF-ETI, 7 PwCF-non ETI, and 32 healthy controls, showing that only the treated group experienced a significant rise in nNO levels, reaching the normal range by follow-up.
- The findings suggest that nNO could be a useful non-invasive biomarker for assessing sinonasal inflammation in cystic fibrosis patients and might correlate
Article Synopsis
- Oral disorders remain a significant global public health issue, and researchers aim to create a new quality of care index (QCI) to measure treatment effectiveness on a population level.
- Using data from the Global Burden of Disease study, the team applied principal component analysis to generate the QCI, which showed an upward trend from 70.5 in 1990 to 74.6 in 2017 without significant gender disparities.
- The highest QCI was found in high-middle SDI countries, while areas like Nicaragua and Sierra Leone had the lowest scores, indicating that improvements in oral care quality have occurred, yet disparities remain across different regions.
Background: Diabetes as the leading cause of mortality and morbidity, have been increased by about 35% from 2011 to 2015 worldwide. The objective of this study was to assess the trend and pattern of diabetes and prediabetes prevalence in Iran and also evaluate the diagnosis and status of diabetes management.
Methods: The results of this study are extracted from the National Stepwise approach to non-communicable disease risk factor surveillance (STEPS), conducted in 2007, 2011, 2016, and 2021 in Iran.
Article Synopsis
- - This study investigated the prevalence of hypertension (HTN) and pre-hypertension (PHTN) in 429 districts across Iran, finding significant inequalities in these health issues among different regions.
- - Data from over 27,000 participants revealed that crude prevalence rates for HTN ranged from 11.5% to 42.2%, while PHTN rates ranged from 19.9% to 56.1%, with varying levels of awareness and treatment coverage.
- - The findings indicate that central regions and females generally had better health outcomes, suggesting that policymakers should focus on addressing these disparities in resources and hypertension management.
Article Synopsis
- - The study evaluated injury incidence and risk factors in Iran using data from the 2021 STEPS Survey, involving over 27,000 participants across urban and rural areas.
- - Findings indicated that 5.5% reported injuries in the past year, with falls being the most common cause, and higher injury rates among males; factors like gender and alcohol consumption significantly increased the risk of road traffic injuries.
- - The research highlighted notable geographic disparities in injury rates, with the highest rates in Razavi Khorasan for males and Tehran for females, emphasizing the need for targeted interventions based on location and demographics.
Article Synopsis
- - The study focused on estimating lipid abnormalities in Iranian adults by analyzing demographic data, geographic differences, and risk factors from the 2021 STEPs survey, involving over 18,000 participants aged 25 and older.
- - The results showed a high prevalence of dyslipidemia (81.0%), with specific lipid abnormalities like hypertriglyceridemia at 39.7% and low HDL-C at 68.4%, affecting men and women differently.
- - Factors influencing dyslipidemia included obesity, urban residency, inadequate physical activity, and medical history, with significant variation in prevalence across provinces, particularly high in East Azarbaijan at 85.3%.
Article Synopsis
- - The study investigated diabetes mellitus (DM) and prediabetes in Iran using data from the 2021 Iran STEPS Survey, focusing on awareness, treatment coverage, and adherence to World Health Organization targets.
- - Findings revealed that 14.2% of participants had DM and 24.8% had prediabetes, with treatment coverage at 65% but only 28% achieving good glycemic control (HbA1C < 7%).
- - While diagnosis and statin use were close to global targets, overall glycemic control and blood pressure management were significantly below the desired levels, highlighting insufficient diabetes care in the population.
Article Synopsis
- The 2021 STEPS survey in Iran aimed to gather data on non-communicable diseases (NCDs) while managing the challenges posed by the ongoing COVID-19 pandemic.
- The survey modified its standard procedures, incorporating new COVID-19 safety measures, and included a substantial number of participants across its three phases—27,874 in the first phase.
- The results demonstrated the survey's strong representativeness at national and provincial levels, showcasing an effective approach to conducting health research during a crisis.
Article Synopsis
- The WHO STEPwise approach to NCD risk factor surveillance (STEPS) in Iran has been conducted since 2005, with the latest round in 2016 assessing population characteristics and diabetes prevalence among subjects aged 25 and older.
- The 2016 results indicated that approximately 10.6% of the population had diabetes, with a notable portion (2.7%) unaware of their condition, while around 15.2 million individuals were identified as having prediabetes.
- The study also found that more than half of self-reported diabetes patients were under good glycemic control, but a significant percentage experienced poor diabetes management, highlighting a growing public health concern in Iran.
Article Synopsis
- * The survey involved nearly 28,000 Iranian adults, revealing an overall smoking prevalence of 14.01%, with higher rates in men (25.88%) compared to women (4.44%).
- * Second-hand smoking is also a concern, with 24.64% of individuals exposed at home and 19.49% at work, highlighting the ineffectiveness of current tobacco control policies and the need for stronger interventions.
Article Synopsis
- The Iran Cohort Study (ICS) is an observational study aimed at understanding risk factors associated with non-communicable diseases (NCDs) in Iran, with a focus on evidence-based prevention and management.
- Data collection began with the STEPwise Approach to NCD Risk Factor Surveillance survey in 2016, and follow-ups are conducted via phone to assess the impact of various risk factors over three years.
- The study aims to produce a comprehensive data bank, detailed reports on risk factors, and policy recommendations to enhance health programs in Iran, marking it as the first national representative study of its kind in the region.
Background: The intermediate metabolites associated with the development of atherosclerotic cardiovascular disease (ASCVD) remain largely unknown. Thus, we conducted a large panel of metabolomics profiling to identify the new candidate metabolites that were associated with 10-year ASCVD risk.
Methods: Thirty acylcarnitines and twenty amino acids were measured in the fasting plasma of 1,102 randomly selected individuals using a targeted FIA-MS/MS approach.
Background: We aimed to estimate the prevalence of physical inactivity in all districts of Iran and the disparities between subgroups defined by various measures.
Methods: Small area estimation method was employed to estimate the prevalence of physical inactivity in districts based on the remaining districts in which data on the level of physical inactivity were available. Various comparisons on the estimations were done based on socioeconomic, sex, and geographical stratifications to determine the disparities of physical inactivity among districts of Iran.
Background: Prostate cancer (PCa) is one of the most prevalent cancers worldwide, with a significant burden on societies and healthcare providers. We aimed to develop a metric for PCa quality of care that could demonstrate the disease's status in different countries and regions (e.g.
View Article and Find Full Text PDFWorld-Health-Organization's PEN package proposes a minimum set of cost-effective interventions for early diagnosis and management of Non-Communicable-Disease (NCD). IraPEN (the PEN package implemented in Iran), adopted from PEN and Iran National Action Plans for NCDs, addresses challenges regarding NCD prevention and control. IraPEN was piloted in four districts of Iran.
View Article and Find Full Text PDFBackground: Alcohol consumption is a public health concern which is illegal in Iran. Moreover, due to cultural and religious beliefs, the available population-based research findings on alcohol consumption are inadequate. We aimed to provide an estimate on alcohol consumption using a large-scale population-based survey in Iran.
View Article and Find Full Text PDFBackground: Insufficient physical activity (IPA) is a significant risk factor for various non-communicable diseases. The Iran action plan is a 20% reduction in IPA. Therefore, we aimed to describe the age and sex pattern of physical activity domains, IPA, the intensity of physical activity, sedentary behavior, and their associates at Iran's national and provincial levels in 2021.
View Article and Find Full Text PDFBackground: Identification of metabolomics profile in subjects with different blood pressure, including normal blood pressure, elevated blood pressure, stage 1 hypertension, and stage 2 hypertension, would be a promising strategy to understand the pathogenesis of hypertension. Thus, we conducted this study to investigate the association of plasma acylcarnitines and amino acids with hypertension in a large Iranian population.
Methods: 1200 randomly selected subjects from the national survey on the Surveillance of Risk Factors of Non-Communicable Diseases in Iran (STEPs 2016) were divided into four groups based on the ACC/AHA hypertension criteria: normal blood pressure (n = 293), elevated blood pressure (n = 135), stage 1 hypertension (n = 325), and stage 2 hypertension (n = 447).
Background: Obesity and its increasing burden have become an urgent health problem all over the world. Benefiting from a national representative sample, the present study aimed to estimate the distribution of body mass index (BMI) levels and its association with metabolic and lifestyle risk factors in an Iranian adult population by sex, age, and geographical distribution.
Methods: This study involves a national survey of noncommunicable disease risk factor surveillance (STEPs) in Iran.
Background: The determinants and correlates of severe mental disorders are less understood compared to the common mental disorders, both in the world and in Iran. In this study, we aimed to identify a wide range of determinants of severe stress, severe anger, and severe sadness among Iranian population.
Methods: This study is part of a large nationwide cross-sectional survey entitled STEPs conducted using a comprehensive questionnaire to determine the prevalence of main preventable risk factors of non-communicable diseases (NCDs) in Iran by age and sex groups in 2016.
Background: The increasing burden of hypertension in low- to middle-income countries necessitates the assessment of care coverage to monitor progress and guide future policies. This study uses an ensemble learning approach to evaluate hypertension care coverage in a nationally representative Iranian survey.
Methods: The data source was the cross-sectional 2016 Iranian STEPwise approach to risk factor surveillance (STEPs).
Background: Effective equity-focused health policy for hypertension in low- and middle-income countries (LMICs) requires an understanding of the condition's current socioeconomic gradients and how these are likely to change in the future as countries develop economically.
Objectives: This cross-sectional study aimed to determine how hypertension prevalence in LMICs varies by individuals' education and household wealth, and how these socioeconomic gradients in hypertension prevalence are associated with a country's gross domestic product (GDP) per capita.
Methods: We pooled nationally representative household survey data from 76 LMICs.