Effect of Cosmetics Use on the In Vitro Skin Absorption of a Biocide, 1,2-Benzisothiazolin-3-one.

1,2-Benzisothiazolin-3-one (BIT) is a commonly used organic biocide containing an isothiazolone ring. However, it may have adverse effects on human health and its risk needs to be properly evaluated. Dermal exposure is the main route of BIT exposure, and co-exposed substances may affect its absorption.

Anti-Pigmentary Natural Compounds and Their Mode of Action.

Hyper-activated melanocytes are the major cause of skin hyper-pigmentary disorders, such as freckles and melasma. Increasing efforts have been made to search for materials with depigmenting activity to develop functional cosmetics. As a result, numerous materials have been reported to have depigmenting activity but some of them are known to cause unwanted side effects.

Inclusion of inversion symmetry in centroid molecular dynamics: a possible avenue to recover quantum coherence.

Inversion symmetry is included in the operator formulation of the centroid molecular dynamics (CMD). This work involves the development of a symmetry-adapted CMD (SA-CMD), here particularly for symmetrization and antisymmetrization projections. A symmetry-adapted quasidensity operator, as defined by Blinov and Roy [J.