Publications by authors named "YoonAh Park"
Background: Despite advancements in laparoscopic right hemicolectomy for right-sided colon cancer, the choice between functional end-to-end anastomosis and end-to-side anastomosis remains a topic of debate. This study aimed to compare these 2 techniques in terms of postoperative complications and disease-free survival.
Methods: This retrospective analysis included 1,202 patients who underwent laparoscopic right hemicolectomy for nonmetastatic colon cancer at Samsung Medical Center between January 2007 and February 2016.
Article Synopsis
- This study evaluates the effectiveness of colonoscopy in detecting recurrence of stage I colorectal cancer and identifies important recurrence risk factors.
- A retrospective analysis of over 2,200 patients showed high 5-year disease-free survival rates, but a small percentage experienced recurrence, with distinct patterns for colon and rectal cancer.
- The findings suggest that relying only on colonoscopy may miss significant recurrence cases, especially for high-risk patients who may benefit from additional CT scans for better detection and outcomes.
Article Synopsis
- * Methods: It analyzed data from 682 patients treated with neoadjuvant chemoradiotherapy and total mesorectal excision at Samsung Medical Center, using various imaging methods to assess clinical staging and outcomes.
- * Results: Findings indicated that local recurrence occurred in 6.9% of patients, with positive circumferential resection margins, venous invasion, and perineural invasion as key risk factors; patients with complete resections had better survival rates, reinforcing the need for careful monitoring of high-risk individuals.
Article Synopsis
- - The study re-evaluates the assumption that colorectal carcinoma in situ (early-stage cancer) has no risk of spreading to nearby lymph nodes, noting isolated cases of metastasis and recurrence.
- - A retrospective analysis of 1,069 patients showed a low recurrence rate of 0.46%, but some cases revealed lymph node metastasis and distant spread of cancer after surgery.
- - The findings highlight the importance of thorough assessments during diagnosis, as colorectal carcinoma in situ can indeed recur and metastasize, necessitating careful monitoring of patients.
Article Synopsis
- The study focused on identifying prognostic factors for survival in 474 patients with locally advanced rectal cancer who showed strong treatment responses after neoadjuvant chemoradiotherapy.
- The analysis revealed that the circumferential resection margin and the use of adjuvant chemotherapy positively influenced disease-free survival, while the clinical N stage also played a role in overall survival.
- The study recommends close monitoring and consideration of adjuvant chemotherapy for patients with specific risk factors, such as a positive circumferential resection margin and clinical N (+) stage.
Background: The lungs are one of the most common sites for colon cancer metastasis. A few studies reported that approximately 2% to 10% of patients with colon cancer developed pulmonary metastasis. However, among these studies, patient characteristics were heterogeneous, and information on pulmonary metastasis incidence by the TNM stage was scarce.
View Article and Find Full Text PDFBackground: A controversy over the distinction between curiosity and situational interest has recently resurfaced. Nonetheless, empirical research comparing the two is noticeably lacking.
Aims: We attempted to fill this gap and provide much-needed evidence of the distinction between curiosity and situational interest by examining the antecedents and consequences of the two constructs.
Background: The association of a micropapillary pattern with oncologic outcomes has not been fully studied in patients with colon cancer.
Objective: We evaluated the prognostic value of a micropapillary pattern, especially for patients with stage II colon cancer.
Design: A retrospective comparative cohort study using propensity score matching.
Background: Mucinous adenocarcinoma is a rare histologic feature of colorectal cancer and is characterized by oncologic features that are different from those of adenocarcinoma. However, there are conflicting views regarding the prognostic impact of mucinous adenocarcinoma on colon cancer.
Objective: This study aimed to evaluate the prognostic impact of mucinous adenocarcinoma in stage II and III colon cancer.
Background: The protective efficacy of transanal tube for anastomosis was compared with that of diverting stoma in patients with rectal cancer treated with neoadjuvant chemoradiotherapy.
Methods: We included consecutive patients with rectal cancer treated with neoadjuvant chemoradiotherapy and curative surgery from January 2013 to December 2019. The patients were grouped into transanal tube or diverting stoma, according to the protection methods they received.
Background: Bevacizumab is a humanized monoclonal antibody against vascular endothelial growth factor and is used in combination with first-line chemotherapy in the treatment of metastatic colorectal cancer. One of the side effects of bevacizumab is gastrointestinal perforation. This study was designed to identify the effect of bevacizumab in intestinal anastomosis site healing.
View Article and Find Full Text PDFBackground: Depth of tumor is a risk factor for lymph node metastasis in rectal cancer, but impact of yield pathologic T (ypT) stage on lymph node involvement in rectal cancer remains unclear. The aim of this study was to evaluate the correlation between ypT stage and lymph node metastasis.
Methods: From January 2010 to December 2015, 602 patients who were diagnosed with rectal cancer and treated with neoadjuvant chemoradiotherapy (CRT) followed by radical operation were reviewed retrospectively.
Article Synopsis
- Stereopsis is the brain's ability to perceive depth using input from both eyes, which can be affected by visual dysfunction in patients with idiopathic Parkinson's disease (PD) due to dopamine cell degeneration.
- The study involved comparing stereopsis in 12 PD patients and 7 healthy individuals through tests, questionnaires, and brain imaging while watching 3D and 2D movies.
- Results indicated that PD patients had reduced activation in their primary visual cortex compared to controls and no significant difference in their ability to perceive 3D versus 2D, highlighting potential visual processing issues linked to their condition.
Purpose: The purpose of this phase II trial was to evaluate whether the addition of simvastatin, a synthetic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, to preoperative chemoradiotherapy (CRT) with capecitabine confers a clinical benefit to patients with locally advanced rectal cancer (LARC).
Materials And Methods: Patients with LARC (defined by clinical stage T3/4 and/or lymph node positivity) received preoperative radiation (45-50.4 Gy in 25-28 daily fractions) with concomitant capecitabine (825 mg/m2 twice per day) and simvastatin (80 mg, daily).
A Case of Creutzfeldt-Jakob Disease Presented as Rapid Progressive Parkinsonism.
Dement Neurocogn Disord
December 2019
Posterior Type of Alzheimer's Dementia Presenting with Homonymous Hemianopsia.
Dement Neurocogn Disord
December 2017
Background: Alzheimer's disease is a chronic neurodegenerative condition, mostly affecting the medial temporal lobe and associated neocortical structures. In this report, we present a rare clinical manifestation of this disease.
Case Report: A 61-year-old female with word finding difficulty and memory disturbances was diagnosed with Alzheimer's disease.
Robot-assisted surgery for colon cancer has been reported in many studies, most of which worked on right and/or sigmoid colectomy. The aim of this study was to report our experience of robotic transverse colectomy with an intracorporeal anastomosis, provide details of the surgical technique, and present the theoretical benefits of the procedure. This is a retrospective review of prospectively collected data of robotic surgery for colorectal cancer performed by a single surgeon between May 2007 and February 2011.
View Article and Find Full Text PDFPurpose: This study aimed to compare the learning curves and early postoperative outcomes for conventional laparoscopic (CL) and single incision laparoscopic (SIL) right hemicolectomy (RHC).
Methods: This retrospective study included the initial 35 cases in each group. Learning curves were evaluated by the moving average of operative time, mean operative time of every five consecutive cases, and cumulative sum (CUSUM) analysis.
Background And Objectives: The purpose of this study was to determine the risk factors for requirement of surgical or endoscopic interventions for complications caused by the primary tumor during chemotherapy in patients with unresectable metastatic colorectal cancer.
Methods: A total of 259 patients were diagnosed with uncomplicated colorectal cancer with unresectable metastatic disease and underwent chemotherapy as an initial treatment. Among them, 57 (22.
A non-recurrent inferior laryngeal nerve (NRILN), a very rare anatomic variation, is easily damaged during thyroid surgery. Due to impairments during embryonic development, a NRILN is frequently associated with an aberrant subclavian artery. Thus, an aberrant subclavian artery is now regarded as an important vascular anomaly for predicting the presence of a NRILN using various imaging modalities.
View Article and Find Full Text PDFSphincter-preserving operations have increasingly been carried out during the last few decades; nevertheless, temporary defunctioning stoma is still being frequently used for low colorectal anastomosis (LCRA) with staplers and hand-sewn coloanal anastomosis (CAA). From 1994 to 2003, 131 consecutive patients with rectal cancer with tumours within 7 cm from the anal verge underwent LCRA or CAA without defunctioning stoma. Anastomotic complications and treatment were compared between the groups.
View Article and Find Full Text PDFRadiation-induced hemorrhagic proctitis (RIHP) is a serious complication of pelvic irradiation, and a 4% formalin solution has been used for 20 years in treating this sequelae. The first case involving formalin application for treatment of RIHP in Korea was reported in 1996, but there are no additional studies beyond this date. Our study reviews the use of formalin instillation and selective application.
View Article and Find Full Text PDFBackground: The prognosis of patients even with the same stage of rectal cancer varies widely. We analyzed the capability of perioperative change of serum carcinoembryonic antigen (CEA) level for predicting recurrence and survival in rectal cancer patients.
Methods: We reviewed 631 patients who underwent potentially curative resection for stage II or III rectal cancer.