Importance: The neuropathological links underlying the association between changes in liver function and AD have not yet been clearly elucidated.
Objective: We aimed to examine the relationship between liver function markers and longitudinal changes in Alzheimer's disease (AD) core pathologies.
Design: Data from the Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease, a longitudinal cohort study initiated in 2014, were utilized.
This study explores the enhanced adsorption performance of activated carbon felt (ACF) for Cu(II) and Cd(II) ions, achieved using a dual-synergistic approach combining MnO coating and plasma treatment. ACF's intrinsic properties, including a high surface area (~ 1000-2000 m²/g), large porosity, and excellent mechanical stability, make it a promising material for environmental applications. However, its limited surface functional groups hinder its adsorption efficiency for heavy metals.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Clin Psychopharmacol Neurosci
November 2024
Objective: Previous studies have reported that vitamin D deficiency increased the risk of Alzheimer's disease (AD) dementia in older adults. However, little is known about how vitamin D is involved in the pathophysiology of AD. Thus, this study aimed to examine the association and interaction of serum vitamin D levels with AD pathologies including cerebral beta-amyloid (Aβ) deposition and neurodegeneration in nondemented older adults.
View Article and Find Full Text PDFThe contamination of water sources by pharmaceutical compounds presents global environmental and health risks, necessitating the development of efficient water treatment technologies. In this study, the synthesis, characterization, and evaluation of a novel graphitic carbon nitride-calcined (Fe-Ca) layered double hydroxide (gCN-CLDH) composite for electrochemical degradation of sulfamethoxazole (SMX) in water yielded significant outcomes are reported. SEM, XRD, FTIR, and XPS analyses confirmed well-defined composite structures with unique morphology and crystalline properties.
View Article and Find Full Text PDFBackground: Altered thyroid hormone levels have been associated with increased risk of Alzheimer's disease (AD) dementia and related cognitive decline. However, the neuropathological substrates underlying the link between thyroid hormones and AD dementia are not yet fully understood. We first investigated the association between serum thyroid hormone levels and in vivo AD pathologies including both beta-amyloid (Aβ) and tau deposition measured by positron emission tomography (PET).
View Article and Find Full Text PDFThe remediation of diesel-contaminated soil is a critical environmental concern, driving the need for effective solutions. Recently, the methodology of Non-thermal Atmospheric Plasma (NTAP) technology, which is equipped with a Dielectric Barrier Discharge (DBD) electrode and has become a feasible approach, was proven to be viable. The reactive species from the plasma were exposed to the contaminated soil in this investigation using the NTAP technique.
View Article and Find Full Text PDFDeveloping effective water treatment materials, particularly through proven adsorption methods, is crucial for removing heavy metal contaminants. This study synthesizes a cost-effective three-dimensional material encapsulating graphitic carbon nitride-layered double oxide (GCN-LDO) in sodium alginate (SA) through the freeze-drying method. The material is applied to remove uranium (U(VI)) and cadmium (Cd(II)) in real water systems.
View Article and Find Full Text PDFBackground: Growing evidence suggests that not only cerebrovascular disease but also Alzheimer's disease (AD) pathological process itself cause cerebral white matter degeneration, resulting in white matter hyperintensities (WMHs). Some preclinical evidence also indicates that white matter degeneration may precede or affect the development of AD pathology. This study aimed to clarify the direction of influence between in vivo AD pathologies, particularly beta-amyloid (Aβ) and tau deposition, and WMHs through longitudinal approach.
View Article and Find Full Text PDFSci Rep
February 2024
This study synthesized a highly efficient KOH-treated sunflower stem activated carbon (KOH-SSAC) using a two-step pyrolysis process and chemical activation using KOH. The resulting material exhibited exceptional properties, such as a high specific surface area (452 m/g) and excellent adsorption capacities for phenol (333.03 mg/g) and bisphenol A (BPA) (365.
View Article and Find Full Text PDFThe synthesis and characterization of graphitic carbon nitride (GCN) and its composites with calcined layered double hydroxide (CLDH) were examined in this investigation. The goal was to assess these composites' maximum adsorption capacity (q) for U(VI) ions in wastewater. Several different characterization methodologies were utilized to examine the fabricated substances.
View Article and Find Full Text PDFRemoving volatile organic compounds (VOCs) from aqueous solutions is critical for reducing VOC emissions in the environment. Activated carbons are widely used for removal of VOCs from water. However, they show less application feasibility and low removal due to less surface area.
View Article and Find Full Text PDFIn this study, first time the combination of composites with Phytic acid (PA) as the organic binder cross-linker is reported. The novel use of PA with single and double conducting polymers (polypyrrole (Ppy) and polyaniline (Pani)) were tested against removal of Cr(VI) from wastewater. Characterizations (FE-SEM, EDX, FTIR, XRD, XPS) were performed to study the morphology and removal mechanism.
View Article and Find Full Text PDFIn this study, a graphene oxide-based lanthanum hydroxide/chitosan foam (CSGOL foam) was synthesized for arsenate (As(V)) remediation in surface water. The synthesized CSGOL foam texture and purity was assessed using scanning electron microscopy (SEM), Brunauer-Emmett-Teller (BET) surface area, X-ray diffraction (XRD), thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FT-IR), and X-ray photoelectron spectroscopy (XPS) studies. The results proved that the foam was highly porous, stable, and had high surface functionality that facilitated adsorption for water pollutant removal.
View Article and Find Full Text PDFLittle is known about the association between meal frequency and Alzheimer's disease (AD) in humans. We tested the hypothesis that low meal frequency (LMF) is associated with reduced AD pathology in human brain, and additionally investigated the mediation of serum ghrelin, a hunger-related hormone, for the association. A total of 411 non-demented older adults were systematically interviewed to identify their dietary patterns including meal frequency and underwent multi-modal neuroimaging for cerebral beta-amyloid (Aβ) and tau deposition, glucose metabolism, and cerebrovascular injury.
View Article and Find Full Text PDFThe bioaccumulation, non-biodegradability, and high toxicity of Cd(II) and U(VI) in water is a serious concerns. Manganese ferrite/graphene oxide (GMF) nanocomposites were synthesized, characterized, and used to efficiently remove Cd(II) and U(VI) from an aqueous solution in this study. X-ray diffraction (XRD) and X-ray photoemission spectroscopy (XPS) analyses, respectively, confirmed the formation of GMF and the adsorptive removal mechanism.
View Article and Find Full Text PDFBenzo[a]pyrene (BaP) is a major indicator of soil contamination and categorized as a highly persistent, carcinogenic, and mutagenic polycyclic aromatic hydrocarbon. An advanced peroxyacid oxidation process was developed to reduce soil pollution caused by BaP originating from creosote spills from railroad sleepers. The pH, organic matter, particle size distribution of soil, and concentrations of BaP and heavy metals (Cd, Cu, Zn, Pb, and As) in the BaP-contaminated soils were estimated.
View Article and Find Full Text PDFOwing to the ubiquitous existence of detrimental heavy metals in the environment, simple adsorption-oriented approaches are becoming increasingly appealing for the effective removal of Pb and Cr from water bodies. These techniques use nanocomposites (NC) of reduced graphene oxide (rGO) and MnO (rGO-MnO), they employ a hydrothermal technique featuring NaBH and NaOH solutions. Here, spectroscopic and microscopic instrumental techniques were used to evaluate the morphological and physicochemical characteristics of prepared reduced graphene oxide manganese oxide (rGO-MnO), revealing that it possessed a well-defined porous structure with a specific surface area of 126 m g.
View Article and Find Full Text PDFHeavy metals are perceived as a significant environmental concern because of their toxic effect, bioaccumulation, and persistence. In this work, a novel sodium alginate (SA) and carboxymethylcellulose (CMC) entrapped with fly ash derived zeolite stabilized nano zero-valent iron and nickel (ZFN) (SA/CMC-ZFN), followed by crosslinking with CaCl, is synthesized and applied for remediation of Cu(II) and Cr(VI) from industrial effluent. The characterization of the adsorbent and its surface mechanism for removing metals were investigated using advanced instrumental techniques, including XRD, FT-IR, SEM-EDX, BET, and XPS.
View Article and Find Full Text PDFUranium (U(VI)) and thorium (Th(IV)) ions produced by the nuclear and mining industries cause water pollution, thereby harming the environment and human health. In this study, gadolinium oxide-decorated polyvinyl alcohol-graphene oxide composite (PGO-Gd) was developed using a simple hydrothermal process to treat U(VI) and Th(IV) ions in water. The developed material was structurally characterized by highly advanced spectroscopy and microscopy techniques.
View Article and Find Full Text PDFPb(II) is a heavy metal that is a prominent contaminant in water contamination. Among the different pollution removal strategies, adsorption was determined to be the most effective. The adsorbent and its type determine the adsorption process's efficiency.
View Article and Find Full Text PDFBiosorption using modified biochar has been increasingly adopted for the sustainable removal of uranium-contaminated from an aqueous solution. In this research study, the facile preparation and surface characteristics of magnetized biochar derived from waste watermelon rind to treat U(VI) contaminated water were investigated. The porosity, specific surface area, adsorption capacity, reusability, and stability were effectively improved after the magnetization of biochar.
View Article and Find Full Text PDFThis study utilized a facile and scalable one-pot wet impregnation method for Hg(II) adsorption to prepare sulfur-anchored palm shell waste activated carbon powder (PSAC-S). The experimental results revealed that the sulfur precursors promote the surface charge on the PSAC and enhance Hg(II) removal via the NaS > NaSO > CHCSNH sequence. PSAC-S prepared using NaS had significant Hg(II) sorption efficiencies, achieving a maximum sorption capacity of 136 mg g from the Freundlich model.
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