Publications by authors named "Yoon J Cho"

Background: Recently, the phase angle (PhA) has emerged as an essential indicator of cellular health. Most studies have examined its association with physiological conditions, such as sarcopenia, frailty, and physical function, in older populations. Simultaneously, growing attention is being paid to the clinical relevance of segmental PhAs for future applications.

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Background/objectives: Since the initial approach towards the clinical presentation of soft-tissue masses is challenging for frontline physicians, some countries use clinical practice guidelines. Proper imaging work-up is crucial to differentiate between soft-tissue tumors. Recently, ultrasonography and magnetic resonance imaging (MRI) have been widely used.

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Study Design: A prospective study.

Purpose: To diagnose scoliosis, a visit to the hospital for radiography is typically necessary. In such cases, children with scoliosis are exposed to radiation, which may place their health at risk.

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  • This study explored how gait (walking pattern) in adolescents with idiopathic scoliosis relates to their spinal alignment, comparing 80 AIS patients to 80 healthy controls.
  • Results showed significant differences in multiple gait metrics and spinal alignment characteristics between the two groups, particularly in factors like gait speed and thoracic kyphosis.
  • Correlation analysis indicated that certain spinal alignment parameters (like pelvic tilt and sacral slope) closely predict aspects of gait, especially step length and gait asymmetry among AIS patients.
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  • - This study aimed to explore how regular physical activity (PA) before and after a dementia diagnosis affects the risk of death, with a focus on different levels of exercise intensity (light, moderate, vigorous).
  • - Researchers analyzed data from over 60,000 individuals diagnosed with dementia using health examination records and found that higher PA levels were significantly linked to lower mortality risk, with those maintaining regular activity having the lowest risk.
  • - The results indicated that starting any form of PA after a dementia diagnosis led to at least a 20% reduction in mortality risk, suggesting that encouraging physical activity could improve survival for those with dementia.
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To elucidate the relationship between pain and cognitive decline in adults aged ≥60 years using data from the Korean Longitudinal Study of Aging survey. We included 3,287 older adults aged ≥60 years with a Korean Mini-Mental State Examination score ≥24. We assessed the presence of pain and pain interference using self-administered questionnaires.

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  • The study investigates the impact of maternal COVID-19 infection during pregnancy on the neurodevelopmental outcomes of children at 12, 18, and 24 months of age.
  • It utilizes data from the ASPIRE trial, which involved a diverse cohort of over 2,000 pregnant individuals from all states and Puerto Rico, who were enrolled remotely during the pandemic.
  • Results show that children exposed to maternal COVID-19 had a higher prevalence of abnormal developmental scores compared to unexposed children, particularly at 12 months, indicating a potential link between the infection and developmental delays.
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  • - Conservative treatment for lateral head fractures of the great toe in children often leads to issues like hallux valgus interphalangeus (HVIP), making surgical intervention necessary for late-diagnosed cases.
  • - This study involved nine cases that underwent surgery with open reduction and Kirchner wire fixation, with an average delay of 2.9 years from injury to surgery, showcasing challenges and varied causes of the injuries.
  • - Post-surgery results were positive, with improved HVIP angles, American Orthopedic Foot and Ankle Society (AOFAS) scores, and joint motion, indicating that even late-diagnosed fractures can achieve successful treatment outcomes.
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  • A case report details a 27-year-old woman with tuberous sclerosis who experienced spontaneous uterine rupture, leading to emergency surgery where they discovered damage consistent with lymphangioleiomyomatosis.
  • The case emphasizes the need for early diagnosis and monitoring in women of reproductive age due to risks associated with estrogen, highlighting the importance of thorough evaluations in complicated medical situations.
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  • The study evaluated the reliability and validity of the Korean version of the Scoliosis Japanese Questionnaire-27 (SJ-27) by translating and adapting it for Korean-speaking patients.
  • It involved administering the Korean SJ-27 along with the validated Scoliosis Research Society-22 (SRS-22) to 140 patients with idiopathic scoliosis in braces.
  • Results showed high reliability and internal consistency of the SJ-27, with significant correlations to the SRS-22, confirming it as a suitable tool for assessing scoliosis outcomes among these patients.
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  • Smoking cessation can lead to weight gain, which may increase the risk of developing metabolic syndrome (MS), but results on this relationship have been inconsistent in previous studies.
  • A meta-analysis of 24 relevant studies found that ex-smokers had a higher risk of MS compared to active smokers, while the risk was not significantly different for male ex-smokers.
  • The analysis indicated that the risk of MS in men increased if the cessation period was 15 years or less but slightly decreased if the cessation period extended beyond 15 years.
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  • A new AI model was created to predict knee implant sizes for surgeries, making the process faster and easier for surgeons.
  • The model was trained on x-ray images from 714 patients and used data augmentation to enhance training data without relying on clinical or demographic info.
  • Results showed the model had high accuracy, with micro F1-scores of 0.91 for femur and 0.87 for tibia, indicating its potential to streamline preoperative procedures in knee surgeries.
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Background: To examine the association between glycemic status and all-cause mortality risk among individuals with dementia.

Methods: We enrolled 146,832 individuals aged 40 and older with dementia as identified through the Korean National Health Insurance Service health screening test between 2008 and 2016. Mortality status was evaluated at the end of 2019.

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Background: We investigated the normal development of the secondary ossification centers of the acetabulum, focusing on their location and the amount of acetabular coverage increased by them.

Methods: We enrolled 132 patients who were 7 to 16 years of age and had no pelvic deformity but did have ≥1 os ischium, os ilium, and/or os pubis on abdominal or pelvic computed tomographic (CT) scans. The locations of the ossification centers were evaluated by adopting an orientation using 0° for the superior acetabulum, 90° for the anterior acetabulum, 180° for the inferior acetabulum, and 270° for the posterior acetabulum, on a reconstructed 3-dimensional (3D) CT image.

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Background: Quantitative myocardial blood flow (MBF) on positron-emission tomography myocardial perfusion imaging is a measure of the overall health of the coronary circulation. The ability to adequately augment blood flow, measured by myocardial blood flow reserve (MBFR), is associated with lower major adverse cardiovascular events and all-cause mortality. The age-specific ranges of MBFR in patients without demonstrable coronary artery disease have not been well established.

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Interest in energy-to-X and X-to-energy (where X represents green hydrogen, carbon-based fuels, or ammonia) technologies has expanded the field of electrochemical conversion and storage. Solid oxide electrochemical cells (SOCs) are among the most promising technologies for these processes. Their unmatched conversion efficiencies result from favorable thermodynamics and kinetics at elevated operating temperatures (400-900 °C).

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Purpose: We aimed to develop and investigate positional reproducibility using a fixation device (Unity Brain tumor Immobilization Device [UBID]) in patients with brain tumor undergoing magnetic resonance (MR)-guided radiation therapy (RT) with a 1.5 Tesla (T) MR-linear accelerator (MR-LINAC) to evaluate its feasibility in clinical practice and report representative cases of patients with central nervous system (CNS) tumor.

Materials And Methods: Quantitative analysis was performed by comparing images obtained by placing only the MR phantom on the couch with those obtained by placing UBID next to the MR phantom.

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  • * Researchers are exploring whether DNA methylation profiles differ between soft tissue sarcomas and normal tissues, among different subtypes of these tumors, and in relation to tumor grade, highlighting a need for further study in this area.
  • * A study was conducted with 85 patients treated for soft tissue sarcomas from 2019 to 2022, resulting in 39 tissue samples (34 from sarcomas and 5 from normal muscle) being analyzed for genomic differences that might aid in diagnosis and treatment strategies
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Introduction: Researchers have highlighted concerns regarding the limited diagnostic utility and ecological validity of the Continuous Performance Test (CPT). Recent advancements in VR-based CPTs have attempted to address these concerns by simulating real-life scenarios and enhancing attention deficit hyperactivity disorder (ADHD) diagnosis; however, certain areas require improvement for obtaining reliable data from both healthy individuals and those with ADHD. To tackle these issues, we developed an enhanced VR-based CPT program featuring four distinct difficulty levels, advancing toward home-based assessment.

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  • - The study aimed to explore whether mothers' COVID-19 vaccinations during pregnancy impacted their children's developmental scores at ages 12 and 18 months, focusing on neurodevelopmental outcomes.
  • - Conducted through a remote prospective cohort study, it involved 2,487 pregnant individuals from all 50 states, who provided data through the Ages and Stages Questionnaire (ASQ-3) assessing various developmental skills.
  • - Results indicated similar rates of developmental delays among infants exposed to maternal COVID-19 vaccination compared to those not exposed, with no statistically significant differences in the outcomes after 12 and 18 months.
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Purpose: Many studies have been conducted to evaluate the effects of nail shape, design, or length on the treatment of intertrochanteric fractures. However, the clinical implications of the nail diameter remain unclear.

Methods: This study was conducted with 191 patients aged ≥ 50 years with unilateral intertrochanteric fractures treated with the same type of short cephalomedullary nail and followed for at least one year.

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Air pollution is an environmental risk factor linked to multiple human diseases including cardiovascular diseases (CVDs). While particulate matter (PM) emitted by diesel exhaust damages multiple organ systems, heart disease is one of the most severe pathologies affected by PM. However, the in vivo effects of diesel exhaust particles (DEP) on the heart and the molecular mechanisms of DEP-induced heart dysfunction have not been investigated.

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The electroreduction of CO plays an important role in achieving a net-zero carbon economy. Imidazolium cations can be used to enhance the rate of CO reduction reactions, but the origin of this promotion remains poorly understood. In this work, we show that in the presence of 1-ethyl-3-methylimidazolium (EMIM), CO reduction on Ag electrodes occurs with an apparent activation energy near zero, while the applied potential influences the rate through the pre-exponential factor.

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While interest in developing the human microbiome as a biomarker for attention-deficit hyperactivity disorder (ADHD) is increasing, there has been limited exploration in utilizing urine samples. In this study, we analysed urine microbiome profiles by extracting 16S ribosomal DNA from purified bacteria-derived extracellular membrane vesicles obtained from urine samples. Sequencing libraries were constructed by amplifying V3-V4 hypervariable regions sequenced using Illumina MiSeq.

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Backgrounds: Determining the precise localization of diseased physes is crucial for guiding the treatment of growth disturbances. Conventional radiography, computed tomography (CT), and magnetic resonance imaging only provide information on physeal anatomy. Planar bone scintigraphy and bone single-photon emission computed tomography (SPECT) resolutions are suboptimal for clinically managing growth disturbances.

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