Publications by authors named "Yongzhou Liang"
Background: This study utilized large-scale population data from the National Health and Nutrition Examination Survey (NHANES) to elucidate the relationship between the Klotho protein and metabolic syndrome along with its components. We further investigated the possible mediating effect of inflammation on these relationships. Our objective was to identify biomarkers for risk stratification and potential therapeutic targets for metabolic syndrome.
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- The study investigates the relationship between heavy metal exposure and blood pressure in children and adolescents, addressing gaps in prior research regarding the effects of various factors like body weight and fish consumption.
- Using data from the National Health and Nutrition Examination Survey, researchers analyzed the urinary levels of 12 different metals and their impact on both systolic and diastolic blood pressure, applying various statistical methods to draw conclusions.
- Results indicated that low exposure to metals like lead, mercury, and molybdenum was linked to lower blood pressure, while barium was associated with increased blood pressure; fish consumption amplified the effects of heavy metals on blood pressure levels.
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- Sepsis is a major cause of neonatal death, and researchers created a nomogram to predict early complications in critically ill neonates to enhance treatment timing.* -
- The study analyzed data from 924 neonates diagnosed with sepsis, comparing the effectiveness of the Lasso algorithm and stepwise regression in predicting outcomes, with the Lasso algorithm showing greater accuracy.* -
- Key predictors of 28-day mortality identified include jaundice, corticosteroid use, weight, serum calcium, inotropes, and base excess; further refinement and validation of the nomogram are needed for broader use.*
Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterized by motile ciliary dysfunction and impaired ultrastructure. Despite numerous studies, the genetic basis for about 30% of PCD cases remains to be elucidated. Here, we present the identification and functional analysis of two novel mutations in the gene encoding coiled-coil domain-containing protein 40 (CCDC40), which are found in a familial case of PCD.
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