Advanced Ruthenium-Based Electrocatalysts for NO Reduction to Ammonia.

Ammonia (NH) is widely recognized as a crucial raw material for nitrogen-based fertilizer production and eco-friendly hydrogen-rich fuels. Currently, the Haber-Bosch process still dominates the worldwide industrial NH production, which consumes substantial energy and contributes to enormous CO emission. As an alternative NH synthesis route, electrocatalytic reduction of NO species (NO , NO , and NO) to NH has gained considerable attention due to its advantages such as flexibility, low power consumption, sustainability, and environmental friendliness.

Boosting the Durability of High-Pt-Content Fuel Cell Cathode Catalysts Through TaO Decorating.

Enhancing the durability of carbon-supported platinum catalysts (Pt/C) for the oxygen reduction reaction remains a significant challenge in the field of proton exchange membrane fuel cells (PEMFCs), especially for catalysts with high-Pt contents. Herein, a TaO decorating strategy that is capable of effectively boosting the durability of Pt/C catalysts even with a high-Pt content of 50 wt.% is introduced.

A rapid and specific fluorescent probe based on aggregation-induced emission enhancement for mercury ion detection in living systems.

Mercury is a harmful heavy metal that seriously threatens the environment and organisms. In this study, we combined the aggregation-induced emission mechanism and the advantages of peptides to design a novel tetraphenylene (TPE)-based peptide fluorescent probe, TPE-Cys-Pro-Gly-His (TPE-CPGH), in which the sulfhydryl group of Cys in the peptide chain and the imidazolium nitrogen provided by His were used to mimic the Hg binding site of metalloproteins. The β-fold formed by Pro-Gly was used to promote the spatial coordination of the probe with Hg and the formation of the coordination complex aggregates, these changes led to the "turn on" response to Hg.

Self-assembly synthesis of hollow phosphorus-doped graphitic carbon nitride microboxes for the photodegradation of organic pollutants.

The rational design of photocatalysts with efficiency and stability is highly desirable but remains challenging. Here, we report a supramolecular self-assembly strategy to construct hollow phosphorus-doped g-CN microboxes (PCNMs). Considering the effects of multiple parameters on the structure and activity of samples, the orthogonal design is innovatively introduced to optimize technology parameters for screening high-performance g-CN.

Proximal femoral tumor resection followed by joint prosthesis replacement: a systematic review and meta-analysis.

Background: This study aimed to determine the prognostic outcome of hip joint replacement after resection of proximal femoral tumors by reviewing original studies.

Methods: Two researchers independently searched PubMed, Embase, Cochrane Library, and Web of Science databases from inception to July 17, 2022. Then, the literature was screened by inclusion criteria.

A Unique Chemo-photodynamic Antitumor Approach to Suppress Hypoxia via Ultrathin Graphitic Carbon Nitride Nanosheets Supported a Platinum(IV) Prodrug.

Tumor hypoxia severely restrains the efficiency of irreversible O-consumption photodynamic therapy. The deep hypoxia induced by photodynamic therapy can promote the level of hypoxia inducible factor 1α that participates in many tumor processes and eventually lead to poor therapeutic outcomes. Herein, a chemo-photodynamic antitumor strategy based on ultrathin graphitic carbon nitride nanosheets loaded with a hypoxia-targeting platinum(IV) prodrug is reported.

Effect of Ca and Zr Additions on Microstructure and Mechanical Properties of As-Extruded Mg-3Sn Alloy.

In this paper, the effect of Ca and Zr additions on microstructure and mechanical properties at room temperature of Mg-Sn alloys was investigated by comparison of Mg-3Sn (wt.%) (T3), Mg-3Sn-1Ca (wt.%) (TX31), and Mg-3Sn-1Ca-1Zr (wt.

A Strategy for Efficient Preparation of Genus-Specific Diagnostic Antibodies for Snakebites.

As said by former United Nations Secretary-General Kofi Annan, "Snakebite is the most important tropical disease you've never heard of." Listed as a priority neglected tropical disease by the World Health Organization, snakebite envenoming (SBE) kills in excess of 125,000 people per year. However, due to the complexity and overlap of snake venom compositions, few reliable venom diagnostic methods for genus-/species-specific identification, which is crucial for successful SBE therapy, are available.

microRNA-3646 serves as a diagnostic marker and mediates the inflammatory response induced by acute coronary syndrome.

Acute coronary syndrome (ACS) is one of the main syndromes of coronary artery disease with high mortality. The identification of biomarkers associated with disease occurrence and progression could improve early detection and risk prediction. This study was aimed to reveal the clinical significance and function of miR-3646 in ACS.

[Mesophyll conductance to CO: Methods and current knowledge].

Mesophyll conductance (g), the total conductance of CO diffusion from substomatal cavity to the site of carboxylation within chloroplast, is a major limiting factor for photosynthesis and a key parameter for improving photosynthetic resource use efficiency of crops. Online C discrimination method is an important method for plant eco-physiological studies and a well-established method for measuring g of C3 plants, although it has not been widely used due to challenges in methodology and high demands on experimental facilities. In this review, we summarized the characteristics of commonly used methods for g, introduced the basic theory of the online C discrimination method, namely Farquhar's photosynthetic C discrimination model; systematically introduced the practical measurements, equations and the components of facilities; and reviewed the drivers for variation in g of C3 plants.

Ghrelin prevents articular cartilage matrix destruction in human chondrocytes.

Osteoarthritis (OA) is the most common form of arthritis worldwide. Excessive production of pro-inflammatory cytokines such as interleukin-1β (IL-1β) plays a key role in the pathogenesis of OA. OA is generally characterized by degradation of extracellular matrixes such as type II collagen and aggrecans mediated by matrix metalloproteinases (MMPs) and a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS).

Troxerutin protects against diabetic cardiomyopathy through NF‑κB/AKT/IRS1 in a rat model of type 2 diabetes.

Troxerutin is a bioflavonoid, which can be used to treat venous disorders, thrombosis and cerebrovascular diseases. Recent studies have demonstrated that it may also be used to prevent edemas. However, it is not known whether troxerutin protects against the cardiomyopathic complications of diabetes.

The ultra-rapid synthesis of 2D graphitic carbon nitride nanosheets via direct microwave heating for field emission.

The 2D g-C3N4 nanosheets were ultra-rapidly prepared via a direct microwave heating approach. The as-synthesized g-C3N4 possessed a large surface area, few stacking layers, a large aspect ratio and an enlarged bandgap. As a consequence, the excellent field emission properties of 2D g-C3N4 nanosheets were exhibited with extremely low turn-on fields.

[Anti-angiogenesis of interferon-alpha2b in chronic myeloid leukemia in vitro].

This study was aimed to investigate the anti-angiogenesis of IFN-alpha2b in chronic myeloid leukemia (CML) in vitro by using K562 cell line and human umbilical vein endothelial cells (HUVEC). The levels of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in culture supernatant of K562 cells were determined by ELISA; the expressions of VEGF and bFGF mRNA after treating K562 cells with 10(3), 10(2) and 10 U/ml IFN-alpha2b for 24, 36, 48 hours were detected by real-time RT-PCR; the effects of K562 cell culture supernatant and IFN-alpha2b on proliferation, migration and differentiation of HUVEC in vitro were assayed by MTT, Transwell chamber and tubule formation assay respectively. The results showed that the K562 cells expressed and secreted VEGF and bFGF.