Adjustable focusing property of circular Airyprime beam through Fourier space modulation.

Airyprime beams are known for their powerful autofocusing property, which are further enhanced by the introduction of a circular structure-circular Airyprime beam (CAPB). We derive an asymptotic expression of the CAPB in Fourier space (FS) and verify its accuracy by the numerical Fourier transform (FT) method. Through FS modulation on it, adjustable control of autofocusing property of the FS-modulated CAPB can be achieved, whose lower and upper limits can reach 8.

Cell fate decision by a morphogen-transcription factor-chromatin modifier axis.

Cell fate decisions remain poorly understood at the molecular level. Embryogenesis provides a unique opportunity to analyze molecular details associated with cell fate decisions. Works based on model organisms have provided a conceptual framework of genes that specify cell fate control, for example, transcription factors (TFs) controlling processes from pluripotency to immunity.

Influence of an adjacent tunnel connecting zone shading shed on drivers' eye movement characteristics.

A tunnel shading shed is crucial in improving driving safety as a type of traffic facility to ease the transition of light environments. To study the effect of installation of a shading shed on the visual characteristics of drivers in the connecting zone of the adjacent tunnels, a total of 32 drivers were gathered to perform a real vehicle experiment. The study zone of the adjacent tunnels was divided into three sections: upstream tunnel exit; connecting zone; and downstream tunnel threshold zone.

Using demographic, psychosocial, behavioural and safety-related factors to assess cyclists' behaviour: A comparative approach across 19 countries.

This Data in Brief (DiB) article presents the differences in cycling behaviors related to violations, errors, and positive behaviors by region. The study data were collected by means of a structured questionnaire applied to a full sample of 7,001 participants from 19 countries, distributed over 5 continents. This paper proposes descriptive statistics, as well as common statistical tests.

Partially coherent Pearcey-Gauss source with hyperbolic sine correlation of the spatial spectrum.

By designing the intricate coherence structure, we are able to create a desired beam profile and trajectory. Our research focus lies on the Fourier plane, specifically emphasizing the coherence of spatial frequencies, and we find it can be seen as a constant system response. A theoretical framework is developed, and experimental studies are conducted to generate a light field of the spatial spectrum with a complex correlation using the pseudo-mode superposition method.

Cyanidin prevents cardiomyocyte apoptosis in mice after myocardial infarction.

Myocardial infarction is a worldwide disease with high morbidity and mortality and a major cause of chronic heart failure, seriously affecting patients' quality of life. Natural medicine has been used to cure or prevent cardiovascular disease for decades. As a natural flavonoid, anthocyanidin has been used to treat many diseases due to its antioxidative, anti-inflammatory, and other properties.

The cardioprotective effects of cerium oxide nanoparticles against the poisoning generated by aluminum phosphide pesticide: Controlling oxidative stress and mitochondrial damage.

Background: Aluminum phosphide (AlP) is a well-known toxic compound used as an agricultural pesticide to prevent insect damage to stored crops. However, even if just a small amount was consumed, it caused lasting harm to the human body and, in acute concentrations, death. The current study employed cerium oxide nanoparticles (CeO NPs) to reduce oxidative stress and various harmful outcomes of AlP poisoning.

Comparative study on electroencephalography characteristics of professional and non-professional drivers in tunnel sections: A field investigation.

Background: The tunnel section is a complex traffic scenario and an accident prone area. There are differences in the performance of different driving groups in tunnel environments, which may have an impact on traffic safety.

Objective: To study the differences in the impact of tunnel environment on professional and non-professional drivers.

Highly efficient enhancement and extension of focusing ability for ring Pearcey beam by means of dual-region parabolic trajectory offset modulation.

It is a highly significant area of research to investigate how to effectively enhance the focusing ability of abruptly auto-focusing beams (AAFBs) while extending the focal length. We introduce a dual-region parabolic trajectory offset modulation to auto-focusing ring Pearcey beams (RPBs), presenting a novel, to the best of our knowlege, approach to extend the focal length while greatly enhancing their auto-focusing capabilities. Unlike directly introducing a linear chirp, which inevitably shortens the focal length to enhance the auto-focusing ability and allows only single focusing in the RPBs, our scheme can achieve a multi-focusing effect.

Virtual sources for structured partially coherent light fields.

A virtual source (VS) is a hypothetical source instead of an actual physical entity, but provides a distinctive perspective to understand physical fields in a source-free area. In this work, we generalize the VS theory to structured partially coherent light fields (PCLFs) by establishing the partially coherent inhomogeneous Helmholtz equation, then demonstrate that PCLFs can be generated from the incoherent extended VS in imaginary space. Especially, we put forward an understanding of the Gaussian Schell-model beam, which consists of a group of partially coherent paraxial complex rays.

A systematic review and meta-analysis of the relationship between economic inequality and prosocial behaviour.

How does economic inequality relate to prosocial behaviour? Existing theories and empirical studies from multiple disciplines have produced mixed results. Here we conduct a systematic review and meta-analysis to systematically synthesize empirical studies. Results from 192 effect sizes and over 2.

Particle manipulation with twisted circle Pearcey vortex beams.

In this Letter, we present an approach for particle manipulation utilizing twisted circle Pearcey vortex beams. These beams are modulated by a noncanonical spiral phase, which allows for flexible adjustment of rotation characteristics and spiral patterns. Consequently, particles can be rotated around the beam's axis and trapped with a protective barrier to avoid perturbation.

The interplay between microbial metabolites and macrophages in cardiovascular diseases: A comprehensive review.

The gut microbiome has emerged as a crucial player in developing and progressing cardiovascular diseases (CVDs). Recent studies have highlighted the role of microbial metabolites in modulating immune cell function and their impact on CVD. Macrophages, which have a significant function in the pathogenesis of CVD, are very vulnerable to the effects of microbial metabolites.

Urban-Rural Distinction or Economic Segmentation: A Study on Fear and Inferiority in Poor Children's Peer Relationships.

Peer relationships play an important role in the growth of children. This study offers insights about feelings of fear and inferiority in children's peer relationships. Based on a national survey, the 2018 Construction for Social Policy Support System for Urban and Rural Poor Families in China, initiated by the Ministry of Civil Affairs, and using multiple regression models and a structural equation model, this study discusses whether and how having a rural household registration or being from a poor () family has an isolation effect on fear and inferiority in children's peer relationships.

Analysis of EEG Characteristics of Drivers and Driving Safety in Undersea Tunnel.

To study the influence of the driving environment of an undersea tunnel on driver EEG (electroencephalography) characteristics and driving safety, a real vehicle experiment was performed in the Qingdao Jiaozhou Bay Tunnel. The experimental data of the drivers' real vehicle experiment were collected using an illuminance meter, EEG instrument, video recorder and other experimental equipment. The undersea tunnel is divided into different areas, and the distribution law of driving environment characteristics, EEG characteristics and vehicle speed characteristics is analyzed.

Are conservatives more charitable than liberals in the U.S.? A meta-analysis of political ideology and charitable giving.

Political ideology not only influences political activities, but also apolitical fields such as charitable giving. However, empirical studies regarding political ideology and charitable giving have yielded mixed results. To find out the effect size and explain the variation in effect sizes, we deploy a meta-analysis to estimate the average effect size and examine the potential moderators from four perspectives.

Electrochemical dehydrogenative cross-coupling of xanthenes with ketones.

A new external oxidant-free electrochemical dehydrogenative cross-coupling of xanthenes and ketones for the preparation of functionalized 9-alkyl-9H-xanthenes was developed. This method enables the formation of a new C(sp)-C(sp) bond through release of H as the major byproduct at room temperature, and features mild conditions, high atom economy, excellent functional-group tolerance, scalability and facile applications in pharmaceutical chemistry.

Combination of medical and health care based on digital smartphone-powered photochemical dongle for renal function management.

Currently, the global healthcare market is increasing at high speed with the impendent global aging issue. Healthcare Industry 4.0 has emerged as an efficient solution towards the aging issue since it was integrated with ubiquitous medical sensors, big health processing platform, high bandwidth, speed technologies, and medical services, etc.

Intermolecular Anodic Oxidative Cross-Dehydrogenative C(sp)-N Bond-Coupling Reactions of Xanthenes with Azoles.

A new anode strategy for accessing xanthen-9-azoles via an electrochemical C(sp)-H/N-H cross-coupling of xanthenes with azoles is described. This reaction proceeds efficiently with a broad scope of both xanthenes and N-H-free azoles under metal- and additional oxidant-free conditions and represents a new access to direct incorporation of important N-heterocycle units into the resulting xanthenes.

Large-scale transcriptome comparison reveals distinct gene activations in wheat responding to stripe rust and powdery mildew.

Background: Stripe rust (Puccinia striiformis f. sp. tritici; Pst) and powdery mildew (Blumeria graminis f.

Activity of ulilysin, an archaeal PAPP-A-related gelatinase and IGFBP protease.

Human growth and development are conditioned by insulin-like growth factors (IGFs), which have also implications in pathology. Most IGF molecules are sequestered by IGF-binding proteins (IGFBPs) so that exertion of IGF activity requires disturbance of these complexes. This is achieved by proteolysis mediated by IGFBP proteases, among which the best characterised is human PAPP-A, the first member of the pappalysin family of metzincins.

Protease profiling using a fluorescent domino peptide cocktail.

Five hexapeptides were prepared containing, in a domino-type arrangement, all 25 possible dipeptides between (1) aromatic, (2) hydrophobic, (3) positively charged, (4) negatively charged, and (5) small and polar amino acids. The peptides were fluorescence labeled at the N-terminus with a (7-coumaryl)oxyacetyl group, allowing the selective detection of N-terminal cleavage products. The five peptides were used as a cocktail reagent in an HPLC analysis.

Low background FRET-substrates for lipases and esterases suitable for high-throughput screening under basic (pH 11) conditions.

FRET-based fluorogenic substrates for lipases and esterases were prepared in four steps from commercially available building blocks. The substrates are pyrenebutyric acid monoesters of aliphatic 1,2-diols bearing a dinitrophenylamino group as a quencher. The most enzyme-reactive substrate is ester 2a.