Predictive Factors and Nomogram for Spontaneous Bacterial Peritonitis in Decompensated Cirrhosis Among the Elderly.

Background And Aims: Spontaneous bacterial peritonitis (SBP) represents a significant complication in the decompensated phase of cirrhosis. The challenges in treating SBP and the associated mortality rates are markedly elevated in elderly individuals. Timely detection and intervention for SBP are imperative.

Moderate to severe anemia at admission increases the risk of complications in patients over 60 years with hip fracture.

Background: Anemia frequently occurs in patients with hip fractures and represents a risk factor that can potentially be altered. To evaluate the association between admission anemia and complications in older hip fracture patients while exploring the potential impact of anemia on complications from the perspective of overall, operation and non-operation.

Methods: This retrospective study enrolled in-patients over 60 years old with hip fractures from January 2020 to November 2023.

Assistive device utilization among disabled elderly in China: A cross-sectional study.

Objective: This study aimed to examine the characteristics of assistive device users and influencing factors among disabled elderly in China.

Methods: A total of 13,510 disabled elderly in Sichuan Province were surveyed. Disability was assessed using the Barthel Activities of Daily Living Scale, mental status, sensory perception, and social engagement evaluation.

Irisin alters D-galactose-induced apoptosis by increasing caveolin-1 expression in C2C12 myoblasts and skeletal muscle fibroblasts.

Muscle atrophy and skeletal muscle fibrosis are significant pathological manifestations of primary sarcopenia. The regulation of C2C12 myoblast and skeletal muscle fibroblast apoptosis is associated with these pathological changes. Previous studies have indicated that irisin, the cleaved form of fibronectin type III domain-containing protein 5 (FNDC5), can alleviate primary sarcopenia.

A systematic review and meta-analysis of the clinical efficacy and safety of Chinese patent medicines in treating subacute thyroiditis.

Background: This meta-analysis was performed to evaluate the clinical efficacy and safety of Chinese patent medicines in the treatment of subacute thyroiditis (SAT).

Methods: Chinese databases were searched using a combination of "patent Chinese medicine", "traditional Chinese medicine", "traditional Chinese and western medicine", "sub-thyroiditis", and "subacute thyroiditis". Studies that set Chinese patent medicine treatment of SAT as the experimental group were selected.

A novel charge derivatization-direct infusion mass spectrometry method for the quantitative analysis of C-C fatty acids in rubber seed oil-based biodiesel.

The free fatty acids that contain one to eight carbons (C-C) in biodiesel would affect the quality of biodiesel. It is still a matter of challenge to simultaneously determine the composition of C-C fatty acids in seed oil and seed oil-based biodiesel. Herein, a novel method of charge derivatization coupling with direct infusion mass spectrometry (CD-DIMS) was developed for the determination of the C-C fatty acids in biodiesels.

Falls among older adults with sarcopenia dwelling in nursing home or community: A meta-analysis.

Objectives: To assess and quantify sarcopenia as a risk for falls among community-dwelling older people and nursing home older persons.

Methods: Prospective cohort studies that evaluated the association between sarcopenia and falls in older adults were identified via a systematic literature search of Medline (via Ovid), PubMed, EMBASE, and the Cochrane CENTRAL Library from database inception until October 15, 2018, in English and Chinese.

Results: 10 studies (10,073 participants) were included in the meta-analysis.

Prevalence and associated factors of depressive symptoms among elderly inpatients of a Chinese tertiary hospital.

Background: Depression in the elderly is a serious and often underdiagnosed psychiatric disorder that has been linked to adverse outcomes in the hospital setting. This study aims to evaluate the prevalence of depressive symptoms and associated factors among elderly hospital inpatients.

Methods: The cross-sectional study included 411 consecutively hospitalized patients aged 60 years and older.

NDRG1 disruption alleviates cisplatin/sodium glycididazole-induced DNA damage response and apoptosis in ERCC1-defective lung cancer cells.

Background: Resistance to platinum-based chemotherapy becomes a major obstacle in lung cancer treatment. Compensatory activation of nucleotide excision repair (NER) pathway is the major mechanism accounting for cisplatin-resistance. We aimed at identifying additional regulators in NER-mediated chemoresistance in a hypoxic setting induced by sodium glycididazole (CMNa)-sensitized cisplatin chemotherapy of non-small cell lung cancer (NSCLC).