Publications by authors named "Yongxuan Lai"

Various studies have linked several diseases, including cancer and COVID-19, to single nucleotide variations (SNV). Although single-cell RNA sequencing (scRNA-seq) technology can provide SNV and gene expression data, few studies have integrated and analyzed these multimodal data. To address this issue, we introduce Interpretable Single-cell Multimodal Data Integration Based on Variational Autoencoder (ISMI-VAE).

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Article Synopsis
  • - The Minimum Vertex Weighted Coloring (MinVWC) problem is a complex extension of the NP-hard Minimum Vertex Coloring (MinVC) problem, focusing on minimizing the weights of colors assigned to a graph's vertices rather than just the number of colors.
  • - The paper introduces a new reduction algorithm that uses maximal clique enumeration to efficiently create smaller subgraphs which can help solve the MinVWC problem without the computational heaviness of branching.
  • - Experimental results show that this new algorithm significantly reduces the size of subgraphs for large graphs compared to an existing method, RedLS, and the authors prove that their algorithm's reduction effectiveness matches that of a more exhaustive approach given enough runtime.
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Identifying different types of cells in scRNA-seq data is a critical task in single-cell data analysis. In this paper, we propose a method called ProgClust for the decomposition of cell populations and detection of rare cells. ProgClust represents the single-cell data with clustering trees where a progressive searching method is designed to select cell population-specific genes and cluster cells.

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Background: Accurate precision approaches have far not been developed for modeling mortality risk in intensive care unit (ICU) patients. Conventional mortality risk prediction methods can hardly extract the information in longitudinal electronic medical records (EHRs) effectively, since they simply aggregate the heterogeneous variables in EHRs, ignoring the complex relationship and interactions between variables and the time dependence in longitudinal records. Recently deep learning approaches have been widely used in modeling longitudinal EHR data.

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Vehicular nodes are equipped with more and more sensing units, and a large amount of sensing data is generated. Recently, more and more research considers cooperative urban sensing as the heart of intelligent and green city traffic management. The key components of the platform will be a combination of a pervasive vehicular sensing system, as well as a central control and analysis system, where data-gathering is a fundamental component.

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Data gathering is a key operator for applications in wireless sensor networks; yet it is also a challenging problem in mobile sensor networks when considering that all nodes are mobile and the communications among them are opportunistic. This paper proposes an efficient data gathering scheme called ADG that adopts speedy mobile elements as the mobile data collector and takes advantage of the movement patterns of the network. ADG first extracts the network meta-data at initial epochs, and calculates a set of proxy nodes based on the meta-data.

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