Influence of impact velocity and impact attack angle of bullets on damage of human tissue surrogate -- ballistic gelatin.

Purpose: Terminal performance of a bullet in human body is critical for the treatment of gunshot injury and optimization of bullet design. The effects of the impact velocity (v) and the impact attack angle (δ) of the bullet on its terminal performance was investigated, using a new evaluation method (called expansion method) based on the expansion of cracks and the permanent cavity wall in ballistic gelatin.

Methods: Ballistic gelatin was used to simulate human body.

Diagnostic and Categorization Criteria for Palpitations Below the Heart in Traditional Chinese Medicine: A Delphi Consensus Study.

Objectives: To explore and establish the diagnosis, syndrome classification and syndrome differentiation criteria of palpitations below the heart in traditional Chinese medicine (TCM) in order to lay a foundation for the clinical diagnosis, treatment and research of palpitations below the heart.

Methods: In the early stage of this study, we searched the literature related to palpitations below the heart in TCM in domestic and foreign databases, analyzed the results and developed an expert consultation questionnaire. Using the Delphi method, a survey was conducted by 19 expert TCM practitioners.

Photodegradation of Cationic and Anioic Dyes by pH-Dependent Dispersion of Amphoteric g-C₃N₄ Nanosheets.

g-C₃N₄ nanosheets (NSs) were prepared via H₂SO₄ exfoliation from the bulky g-C₃N₄ and the photocatalytic (PC) activities were investigated comprehensively using Rodamine B (RhB) and Chromotrope 2R (Ch2R) as candidate pollutants. The results showed that the pH value have important functions in the improvement of photodegradation performance of C₃N₄ NSs. RhB as cationic dye could be photodegraded more efficiently under acidic conditions while Ch2R as anionic dye was degraded easily in pH ≥ 11 solution.

Schisandrin A ameliorates MPTP-induced Parkinson's disease in a mouse model via regulation of brain autophagy.

Schisandrin A (Sch A) is one of the principal bioactive lignans isolated from Fructus schisandrae. In this study, we demonstrated its protective effect and biochemical mechanism of action in a 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced mouse model of Parkinson's disease. Sch A significantly ameliorated behavioural abnormalities and increased the number of nigral dopaminergic neurons detected by tyrosine hydroxylase immunohistochemistry.

The experimental and numerical investigation on the ballistic limit of BB-Gun pellet versus skin simulant.

The insufficient recognition of injuries by the BB-gun (regarded as toys for children) has led to its increasing misuse without permission, which has caused many public safety issues. Aiming to enhance the understanding of the injuries by the BB-gun, the experimental and numerical study of BB-Gun pellet penetrating "cowhide + gelatine" composite target was comprehensively carried out. It was confirmed from the experiment that BB-Gun is capable of inflicting severe or fatal wounds to important organs, and perforating the skin or not could be employed to evaluate the safety of BB-guns.

Pharmacokinetics and UPLC-MS/MS of Delsoline in Mouse Whole Blood.

Delsoline, a major alkaloid of Hance, has both a curare-like effect and a ganglion-blocking effect and is used to relieve muscle tension or hyperkinesia. A ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was established for the determination of delsoline in mouse blood, and the pharmacokinetics of delsoline after intravenous administration (1 mg/kg) and intragastric administration (9, 6, and 3 mg/kg) were studied. Gelsenicine served as an internal standard, and a UPLC BEH C18 chromatographic column was used.

Comparison of ballistic impact effects between biological tissue and gelatin.

Gelatin is commonly used in ballistic testing as substitute for biological tissue. Comparison of ballistic impact effects produced in the gelatin and living tissue is lacking. The work in this paper was aimed to compare the typical ballistic impact effects (penetration trajectory, energy transfer, temporary cavity) caused by 4.

Rifle bullet penetration into ballistic gelatin.

The penetration of a rifle bullet into a block of ballistic gelatin is experimentally and computationally studied for enhancing our understanding of the damage caused to human soft tissues. The gelatin is modeled as an isotropic and homogeneous elastic-plastic linearly strain-hardening material that obeys a polynomial equation of state. Effects of numerical uncertainties on penetration characteristics are found by repeating simulations with minute variations in the impact speed and the angle of attack.

Assessment of effect of Zhu-tan Tong-luo decoction on CYP450 isoforms activity of rats.

In order to investigate the effects of Zhu-tan Tong-luo decoction on the metabolic capacity of cytochrome P450 (CYP) enzymes, a cocktail method was employed to evaluate the activities of CYP2B6, CYP2C19, CYP1A2, CYP3A4, CYP2C9, CYP2D6. The rats were randomly divided into acute Zhu-Tan Tong-Luo decoction group (Low, High), chronic Zhu-Tan Tong-Luo decoction group (Low, High) and control group. The acute group rats were given 0.

Clinical efficacy and sEMG analysis of a new traditional Chinese medicine therapy in the treatment of spasticity following apoplectic hemiparalysis.

To investigate the clinical effect and surface electromyography (sEMG) of rehabilitation exercise therapy in combination with total glucosides form Shaoyao Gancao decoction in treating spasticity after apoplectic hemiparalysis. Composite spasticity scale (CSS), Fugl-Meyer assessment (FMA) and modified Barthel index were compared between the exercise only group and the combined therapy group before and 1 month after the treatment to scale muscular tension, function and activities of daily living. Meanwhile, integrate EMG and root mean square (RMS) were used to detect the tension of upper limbs (biceps brachii) and ankles (tibialis anterior muscle and gastrocnemius) after the 1-month treatment.