Strategies for Managing Pediatric Fracture Pain: Assessment, Pharmacological, and Non-Pharmacological Interventions.

Fractures are prevalent among the pediatric population, with approximately 1 in 3 children experiencing at least 1 fracture during childhood. Children are not just little adults; they have unique needs in pain management. With a lack of knowledge in pediatric pain management, medical staff primarily focus on the fractures, often overlooking and inadequately addressing pain.

Synthesis and Characterization of Superhydrophobic Epoxy Resin Coating with SiO@CuO/HDTMS for Enhanced Self-Cleaning, Photocatalytic, and Corrosion-Resistant Properties.

The exceptional corrosion resistance and combined physical and chemical self-cleaning capabilities of superhydrophobic photocatalytic coatings have sparked significant interest among researchers. In this paper, we propose an economical and eco-friendly superhydrophobic epoxy resin coating that incorporates SiO@CuO/HDTMS nanoparticles modified with Hexadecyltrimethoxysilane (HDTMS). The application of superhydrophobic coatings effectively reduces the contact area between the metal surface and corrosive media, leading to a decreased corrosion rate.

The cyclization/rearrangement of α-hydroxy ketones with trifluoromethyl -acylhydrazones to synthesize multi-substituted trifluoromethyloxazolines.

A highly efficient and metal-free [3+2] cyclization/rearrangement reaction toward the synthesis of multisubstituted trifluoromethyloxazolines from α-hydroxyketones and trifluoromethyl -acylhydrazones has been developed. The unprecedented rearrangement of the amide fragment under acidic conditions after cleavage of the N-N bond of acylhydrazones has opened up new avenues for the development of reactions involving trifluoromethyl -acylhydrazones. DFT calculations show that the mechanism involves multiple proton transfer processes.

Clinical Analysis of Surgical Treatment of Senile Intertrochanteric Fracture Based on Intelligent Knowledge of Health Care.

In order to explore the clinical application value of intelligent health care knowledge combined with closed reduction intramedullary nail fixation in elderly patients with intertrochanteric fracture of the femur, a retrospective analysis is performed on 80 elderly patients who received intertrochanteric surgery from January 2019 to January 2021. All patients were divided into study group and control group based on intelligent medical knowledge received or not. During the phase of treatment, both the two groups were treated with closed reduction and intramedullary nailing.

Prediction of the Collapse of Necrotic Femoral Head by CT and X-Ray Examinations before Hip Replacement Based on Intelligent Medical Big Data.

It was to explore the effect of the CT and X-ray examinations before the hip replacement to predict the collapse of the necrotic femoral head under the classification of medical big data based on the decision tree algorithm of the difference grey wolf optimization (GWO) and provide a more effective examination basis for the treatment of patients with the osteonecrosis of the femoral head (ONFH). From January 2019 to January 2021, a total of 152,000 patients with ONFH and hip replacement in the tertiary hospitals were enrolled in this study. They were randomly divided into two groups, the study sample-X group (X-ray examination results) and based-CT group (CT examination results)-76,000 cases in each group.