The Pancharatnam-Berry (PB) phase has revolutionized the design of metasurfaces, offering a straightforward and robust method for controlling wavefronts of electromagnetic waves. However, traditional metasurfaces have fixed PB phases determined by the orientation of their individual elements. In this study, an innovative structural design and integration scheme is proposed that utilizes vanadium dioxide, a phase-change material, to achieve thermally controlled dynamic PB phase control within the metasurface.
View Article and Find Full Text PDFOptical image processing with high operational efficiency has been applied as a pre-processing imaging system for image recognition. Edge-enhanced imaging as a high-efficiency optical image processing method is of great significance for feature extraction and target recognition. However, the edge-enhanced imaging system based on the 4F system and the spatial filter transforms mainly work under coherent light illumination conditions, without continuously zooming to track the spatial position of the target.
View Article and Find Full Text PDFLight field displays reconstruct 3D scenes through integral imaging. However, inefficient light ray acquisition degrades the visual experience, while the fixed position of the exit pupil limits viewer mobility. In this paper, we propose a novel light field acquisition method employing parallax mapping techniques, coupled with adaptive viewport optimization based on eye tracking data.
View Article and Find Full Text PDFMultifocal metalenses are effective elements for longitudinal light field modulation and have important applications in long-focal depth imaging and three-dimensional display. However, the forward design method is subject to destructive interference generated by phase discontinuity, and cannot achieve high-efficiency, tunable multifocal metalenses. Therefore, we propose an efficient and tunable inverse design framework based on the adjoint method and gradient strategy, transforming light field modulation into mathematical optimization of nonlinear constraints.
View Article and Find Full Text PDFBy controlling light fields in subwavelength scales, metasurfaces enable novel ways for miniaturization and integration of spectral imaging system. Metasurfaces supporting quasi bound states in the continuum (quasi-BICs) can control the quality factor and spectral response by changing structural parameters. In this work, we present an ultra-compact multispectral imaging device, whereby spectral modulation is achieved by meta-atoms arrays supporting quasi-BICs.
View Article and Find Full Text PDFIn the realm of active polarization detection systems, the imperative for polarization illumination systems with high-uniformity and predefined-shape irradiance distribution is evident. This paper introduces a novel anamorphic aspheric (AAS) microlens array (MLA) integral polarization homogenizer, incorporating projection MLA (PMLA), condenser MLA (CMLA), polarization film (PF), and a sub-image array (SIA) mask based on Kohler illumination principles. Firstly, the optimal design of an AAS-based projection sub-lens is proposed to facilitate the creation of a short-working-distance, predefined-geometric and sharp polarization irradiance tailoring.
View Article and Find Full Text PDFDeep learning-based computer-generated holography offers significant advantages for real-time holographic displays. Most existing methods typically utilize convolutional neural networks (CNNs) as the basic framework for encoding phase-only holograms (POHs). However, recent studies have shown that CNNs suffer from spectral bias, resulting in insufficient learning of high-frequency components.
View Article and Find Full Text PDFThe immersive augmented reality (AR) system necessitates precise depth registration between virtual objects and the real scene. Prior studies have emphasized the efficacy of surface texture in providing depth cues to enhance depth perception across various media, including the real scene, virtual reality, and AR. However, these studies predominantly focus on black-and-white textures, leaving a gap in understanding the effectiveness of colored textures.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
September 2024
Circular RNAs (circRNAs) play a crucial role in gene regulation and have been implicated in the development of drug resistance in cancer, representing a significant challenge in oncological therapeutics. Despite advancements in computational models predicting RNA-drug interactions, existing frameworks often overlook the complex interplay between circRNAs, drug mechanisms, and disease contexts. This study aims to bridge this gap by introducing a novel computational model, circRDRP, that enhances prediction accuracy by integrating disease-specific contexts into the analysis of circRNA-drug interactions.
View Article and Find Full Text PDFNon-radiative optical modes attracted enormous attention in optics due to strong light confinement and giant Q-factor at its spectral position. The destructive interference of multipoles leads to zero net-radiation and strong field trapping. Such radiationless states disappear in the far-field, localize enhanced near-field and can be excited in nano-structures.
View Article and Find Full Text PDFIn virtual surgical training, it is crucial to achieve real-time, high-fidelity simulation of the tissue deformation. The anisotropic and nonlinear characteristics of the organ with multi-component make accurate real-time deformation simulation difficult. A localized tissue constraint progressive transfer learning method is proposed in this paper, where the base-compensated dual-output transfer learning strategy and the localized tissue constraint progressive learning architecture are developed.
View Article and Find Full Text PDFLight therapy is an effective approach for the treatment of a variety of challenging dermatological conditions. In contrast to existing methods involving high doses and large areas of illumination, alternative strategies based on wearable designs that utilize a low light dose over an extended period provide a precise and convenient treatment. In this study, we present a battery-free, skin-integrated optoelectronic patch that incorporates a coil-powered circuit, an array of microscale violet and red light emitting diodes (LEDs), and polymer microneedles (MNs) loaded with 5-aminolevulinic acid (5-ALA).
View Article and Find Full Text PDFA general method for designing an integral projection system is proposed, including optical design and digital preprocessing based on the mapping within the projection system. The per-pixel mapping between the sub-images and the integral projection image is generated by incorporating an integral projection imaging model as well as the ray data of all sub-channels. By tracing rays for sparsely sampled field points of the central sub-channel and constructing the mapping between the central sub-channel and other sub-channels, the efficient acquisition of ray data for all sub-channels is achieved.
View Article and Find Full Text PDFAccurately reconstructing 4D critical organs contributes to the visual guidance in X-ray image-guided interventional operation. Current methods estimate intraoperative dynamic meshes by refining a static initial organ mesh from the semantic information in the single-frame X-ray images. However, these methods fall short of reconstructing an accurate and smooth organ sequence due to the distinct respiratory patterns between the initial mesh and X-ray image.
View Article and Find Full Text PDFNear-infrared (NIR) spectral information is important for detecting and analyzing material compositions. However, snapshot NIR spectral imaging systems still pose significant challenges owing to the lack of high-performance NIR filters and bulky setups, preventing effective encoding and integration with mobile devices. This study introduces a snapshot spectral imaging system that employs a compact NIR metasurface featuring 25 distinct C symmetry structures.
View Article and Find Full Text PDFAugmented reality (AR) display, as a next-generation innovative technology, is revolutionizing the ways of perceiving and communicating by overlaying virtual images onto real-world scenes. However, the current AR devices are often bulky and cumbersome, posing challenges for long-term wearability. Metasurfaces have flexible capabilities of manipulating light waves at subwavelength scales, making them as ideal candidates for replacing traditional optical elements in AR display devices.
View Article and Find Full Text PDFDue to the intrinsic polarized emission property, polarized emissive materials with anisotropic nanostructures are expected to be potential substitutes for polarizers. Herein, by the template-assisted strategy, well-aligned lead-free metal halide CsCuI nanowire (NW) arrays are fabricated by evaporating the precursor ink in the anodic aluminum oxide (AAO) for polarized emission. The CsCuI/AAO composite film emits highly polarized light with a degree of polarization (DOP) of 0.
View Article and Find Full Text PDFWhile genome-wide association studies (GWAS) have unequivocally identified vast disease susceptibility variants, a majority of them are situated in non-coding regions and are in high linkage disequilibrium (LD). To pave the way of translating GWAS signals to clinical drug targets, it is essential to identify the underlying causal variants and further causal genes. To this end, a myriad of post-GWAS methods have been devised, each grounded in distinct principles including fine-mapping, co-localization, and transcriptome-wide association study (TWAS) techniques.
View Article and Find Full Text PDFObjective: Biliary interventional procedures require physicians to track the interventional instrument tip (Tip) precisely with X-ray image. However, Tip positioning relies heavily on the physicians' experience due to the limitations of X-ray imaging and the respiratory interference, which leads to biliary damage, prolonged operation time, and increased X-ray radiation.
Methods: We construct an augmented reality (AR) navigation system for biliary interventional procedures.
Image-based endoscopy pose estimation has been shown to significantly improve the visualization and accuracy of minimally invasive surgery (MIS). This paper proposes a method for pose estimation based on structure-depth information from a monocular endoscopy image sequence. Firstly, the initial frame location is constrained using the image structure difference (ISD) network.
View Article and Find Full Text PDFBy utilizing a catadioptric system and a calibration Lambertian sample, a compact measurement method of bidirectional reflectance distribution function (BRDF) has been proposed for rapid and accurate measurement. With the help of an ellipsoidal dome mirror, a hyperboloid mirror, and a high-resolution camera, spatial reflectance distributions from reflected directions with a large field of view (FOV) can be obtained. The built-in Lambertian standard allows for real-time calibration to account for fluctuations in the illumination spectrum, effectively reducing the measurement drift and achieving a high accuracy.
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