Clinical value of monitoring cytokine levels for assessing the severity of mycoplasma pneumoniae pneumonia in children.

Background: To investigate the clinical relevance of cytokine levels in assessment of the severity of mycoplasma pneumoniae pneumonia (MPP) in children.

Methods: A retrospective study was conducted on 150 pediatric cases of MPP admitted to a local hospital in China from November 1, 2022 to October 31, 2023. These MPP cases were divided into mild (n=100) and severe (n=50) groups according to the severity of the disease.

[Changes in 25-hydroxyvitamin D3 level in children with Henoch-Schönlein purpura].

Objective: To examine the changes in 25-hydroxyvitamin D [25-(OH)D] level in children with Henoch-Schönlein purpura (HSP) and its clinical significance.

Methods: A total of 92 HSP children were included in this study, and were divided into HSP nephritis (HSPN) group (31 cases) and HSP group (61 cases) based on the presence or absence of HSPN. Alternatively, the patients were divided into purpura alone group (22 cases), purpura with joint symptoms group (joint symptom group, 24 cases), purpura with gastrointestinal symptoms group (gastrointestinal symptom group, 20 cases), and purpura with joint and gastrointestinal symptoms (mixed group, 26 cases) based on their clinical symptoms.