Publications by authors named "Yongsong Fan"
Protective Effect of Adalimumab on Diabetic Nephropathy by Regulating TNF-α Signal Pathway.
Iran J Public Health
December 2021
Article Synopsis
- The study aimed to assess how effective the drug adalimumab is in preventing diabetic nephropathy (DN) using animal models.
- Using Sprague-Dawley rats, researchers induced DN with streptozotocin and treated the rats with adalimumab, measuring changes in blood glucose and urinary albumin levels as indicators.
- Results showed that adalimumab significantly reduced blood glucose and albumin levels, improved kidney function indicators, and lowered the expression of inflammatory molecules, suggesting it works by targeting TNF-α signaling pathways.