Publications by authors named "Yongquan Bai"

Introduction: Obesity, mainly caused by excessive accumulation of visceral fat, excessive fat metabolism will cause hormone secretion imbalance and inflammation and other diseases. is extremely detrimental to human health. Although many treatments are available for obesity, most treatments fail to exert a radical effect or are associated with several side effects.

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Inflammatory bowel disease (IBD) is a refractory chronic inflammatory illness of the gastrointestinal (GI) tract. Macrophage exerts an important role in IBD development. QKI, as an RNA binding protein, was related with inflammatory responses in bacterial infections by regulating the polarization of macrophages.

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Obacunone, a limonin triterpenoid extracted from Phellodendronchinense Schneid or Dictamnus dasycarpusb Turcz plant, elicits a variety of pharmacological effects such as anti-inflammatory, anti-neoplastic, anti-oxidation, and anti-lung-fibrosis ones. However, the anti-fibrotic effect of obacunone and the detailed underlying mechanism in liver fibrosis remain unclear. Liver fibrosis is a debilitating disease threatening human health.

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Article Synopsis
  • A study in Ji'an county, China, assessed cataract prevalence, surgical outcomes, and their social impact on individuals aged 50 and above, finding a cataract prevalence of 23.11%.
  • Among the 5010 individuals examined, cataract surgeries mostly involved modern techniques with a relatively low surgical coverage rate of 32.29% and a social burden of 3.83% due to cataract blindness.
  • Results indicated that older females are at higher risk, and many operated eyes did not achieve optimal visual acuity due to issues like post-capsular opacity and refractive errors.
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Article Synopsis
  • The study aimed to assess the rates of blindness and visual impairments in adults aged 50 and older in Ji'an County, China, using a population-based approach with a large sample size of over 5,000 participants.
  • Results showed a blindness prevalence of 1.56% and moderate to severe visual impairment at 5.29% when considering best corrected visual acuity, with rates rising among older adults, women, and those with lower education levels.
  • The findings highlight cataracts as the leading cause of visual impairment in this demographic, underscoring the need for targeted eye health interventions in the region.
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