Publications by authors named "Yongqing Zhang"

Article Synopsis
  • The study focused on creating peptide-iron complexes from Dictyophora rubrovolvata using ultrasonication and examined their structure, interactions, stability, and antioxidant properties.
  • Optimal production conditions included 90 W ultrasonic power, 4% peptide concentration, a 1:1 mass ratio of peptide to iron chloride, and a pH of 4, achieving a notable iron binding capacity of 66.35 mg/g.
  • The resulting complexes showed enhanced stability against temperature and digestion, improved surface properties, and greater antioxidant activity compared to a hydrothermally produced control, suggesting their potential as innovative iron supplements.
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Transcription factor binding sites (TFBSs) are critical in regulating gene expression. Precisely locating TFBSs can reveal the mechanisms of action of different transcription factors in gene transcription. Various deep learning methods have been proposed to predict TFBS; however, these models often need help demonstrating ideal performance under limited data conditions.

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Short-chain fatty acid ethyl esters (SFAEEs) are critical aroma compounds in Baijiu, and their wider concentration range can lead to differences in the quality grade of Baijiu. Efficiently designing an SFAEEs adsorbent before instrument analysis remains challenging. In this work, nine functionalized covalent organic frameworks (COFs) with different postmodification groups were designed for targeting SFAEEs.

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In the present study, changes in the physicochemical indices, ethyl carbamate (EC) precursor and EC contents, and microbial communities of fermented grains under different fermentation patterns during strong-aroma (SAB) fermentation and changes in EC precursor and EC contents during distillation were investigated to study EC formation during these processes. In detail, the amounts of sorghum added in protocols C and D were half those added in protocols A and B (the normal SAB-producing technology). When fermented for about 30 to 35 days, the fermented grains of protocols A and C were, respectively, remixed with and second-distilled SAB (so-called "", HJJQ) and fermented for about 30 to 40 days.

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Molecular spectroscopy provides intrinsic contrast for in situ chemical imaging, linking the physiochemical properties of biomolecules to the functions of living systems. While stimulated Raman imaging has found successes in deciphering biological machinery, many vibrational modes are Raman inactive or weak, limiting the broader impact of the technique. It can potentially be mitigated by the spectral complementarity from infrared (IR) spectroscopy.

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Hyperspectral and multispectral imaging capture an expanded dimension of information that facilitates discoveries. However, image features are frequently obscured by noise generated from the limited photodamage threshold of the specimen. Although machine learning approaches demonstrate considerable promise in addressing this challenge, they typically require extensive datasets, which can be difficult to obtain.

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  • The study evaluates the quality of Dioscorea opposite Thunb., focusing on polysaccharides as key indicators for yam quality.
  • Researchers extracted polysaccharides from 60 batches using hot water and analyzed their physicochemical properties, identifying important functional groups and molecular weights.
  • HPLC fingerprinting revealed five main monosaccharide components, helping to establish a data reference for quality control of yam polysaccharides.
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This study aimed to extend the storage time of fresh-cut lotus roots. A quantitative evaluation was conducted using the grey-correlation analysis method based on the variation-coefficient weight to observe the treatment of acetic acid (0, 2%, and 5%) and ozone (0, 0.3 mg/L, and 0.

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Maternal exposure to di-n-butyl phthalate (DBP) has been linked to the induction of hypospadias; however, the underlying mechanism remains unclear. Necroptosis is reported to be implicated in developmental malformations. This study aimed to investigate the underlying mechanism of necroptosis in the development of hypospadias.

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Accurately predicting cancer driver genes remains a formidable challenge amidst the burgeoning volume and intricacy of cancer genomic data. In this investigation, we propose HGTDG, an innovative heterogeneous graph transformer framework tailored for precisely predicting cancer driver genes and exploring downstream tasks. A heterogeneous graph construction module is central to the framework, which assembles a gene-protein heterogeneous network leveraging the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and protein-protein interactions sourced from the STRING (search tool for recurring instances of neighboring genes) database.

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Background: Gestational diabetes mellitus (GDM) can lead to various adverse pregnancy outcomes for both mothers and infants, including gestational hypertension, premature rupture of membranes, preterm birth, macrosomia, large for gestational age (LGA) infants, and neonatal hypoglycemia. Previous studies have mainly focused on the overall risk of GDM for adverse maternal and neonatal outcomes, but there has been limited research specifically investigating the relationship between different patterns of abnormal oral glucose tolerance test (OGTT) results and adverse maternal and neonatal outcomes.

Objective: The study aimed to analyze the maternal and neonatal outcomes among GDM women with different OGTT patterns and to explore a new classification method capable of stratifying GDM into high-risk (GDM-HR) and low-risk subtypes based on OGTT results.

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The exciting potential of harnessing the synergy between polysaccharides and bioactive components is attracting significant scientific interest. This research paves the way for the development of novel materials that can improve human health. Therefore, current research is conducted to explore the innovative use of chitosan, polyvinyl alcohol (PVA) complex (CHN-PVA), olive oil-stabilized Pickering emulsions (PEs), and films with multifaceted applications.

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  • Medical genetics has evolved from Mendel's 1865 discoveries to advanced genomics in modern medicine, transforming our understanding of genetic diseases.
  • The term "Genetic Disease" was adopted by the WHO in 1972, while early Chinese genetics textbooks used phrases like "inferior inheritance," highlighting differences in terminology.
  • Recent research reveals that some genetic diseases may arise from mutations in offspring rather than from inherited traits, prompting a need for more precise language to describe genetic conditions in both English and Chinese to enhance cooperation in the field.
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The Yellow River Delta possesses lots of characteristic medicinal plants due to its high salinity and high alkaline environment and Limonium sinense is an iconic plant. However, there are very few studies on L. sinense and its chemical constituents have not been investigated in recent ten years.

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Background: Studies have demonstrated that Sertoli cells are the direct target of Dibutyl phthalate (DBP). However, the role of neurotransmitter receptors is not elucidated.

Methods: Based on our previous studies, maternal Sprague-Dawley (SD) rats in Gestation Day (GD) 14-18 and TM4 cells exposure to 750 mg/kg/day and 100 μM DBP were regarded as treated groups.

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This investigation explored the potential of utilizing alkali-treated corn cob (CC) as a solid carbon source to improve NO and SO removal from flue gas. Leaching experiments unveiled a hierarchy of chemical oxygen demand release capacity: 0.03 mol/L alkali-treated CC > 0.

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Purpose: Radiation therapy stands as an important complementary treatment for head and neck squamous cell carcinoma (HNSCC), yet it does not invariably result in complete tumor regression. The infiltration of immunosuppressive macrophages is believed to mediate the radiation therapy resistance, whose mechanism remains largely unexplored. This study aimed to elucidate the role of immunosuppressive macrophages during radiation therapy and the associated underlying mechanisms.

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As an oleanolic acid derivative, CDDO-Me lacks selectivity for tumors. Based on the high reactive oxygen species (ROS) level in cancer cells, compound was selected from 17 new CDDO arylboronate ester derivatives. A preliminary study revealed that displayed the highest selectivity for cancer cells.

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Lonicerae japonicae flos (LJF), Lonicerae japonicae caulis (LJC), Lonicerae folium (LF) and Lonicerae fructus (LFR) are derived from Thunb., which are formed due to different medicinal parts. The efficacy of the 4 medicinal materials has similarities and differences.

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Introduction: The demand for fresh-cut water chestnuts, a convenient and nutritive vegetable, is increasing in market. However, the slicing of water chestnuts can cause mechanical damage to tissue, which results in quality deterioration. We aimed to select the optimal treatment through a comprehensive comparison of the preservation effect of acetic acid, which could prolong the shelf life of fresh-cut water chestnuts and improve their storage quality.

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Abnormal relaxation and contraction of intestinal smooth muscle can cause various intestinal diseases. Diarrhea is a common and important public health problem worldwide in epidemiology. Zingiber officinale Roscoe (fresh ginger) has been found to treat diarrhea, but the material basis and mechanism of action that inhibits intestinal peristalsis remain unclear.

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