Hypertension is one of the main risk factors for cardiovascular disease and causes widespread morbidity and mortality worldwide. The aim of this work was to screen the fruit with high angiotensin I-converting enzyme (ACE) inhibitory activity and kallikrein (KLK) promotion activity by three different extraction methods from 22 kinds of fruits. Results showed that the aqueous extracts of fresh kiwifruit significantly inhibited ACE activity (47.
View Article and Find Full Text PDFMicrobiota-derived tryptophan metabolites are essential signals for maintaining gut homeostasis, yet the potential contribution to modulating gut microbiota has been rarely investigated. In this study, ZJ316 (CCTCC No. M 208077) with a high production (43.
View Article and Find Full Text PDFFront Microbiol
November 2022
The recent surge in demand for natural preservatives has ushered in a new era of research into novel bacteriocins capable of effectively combating food-borne infections. In this study, the bacteriocin from ZFM216, which has a molecular mass of 11851.9 Da, was purified using macroporous resin, gel chromatography, and reversed-phase high performance liquid chromatography.
View Article and Find Full Text PDFThe study aimed to develop a HPLC method for ephedrine, hesperidin, and baicalin in Lung-Ventilating-Regulating Oral Liquid. The three active constituents were identified in an Agilent TC-C18 (2) chromatographic column (250mm × 4.6mm, 5μm), with 0.
View Article and Find Full Text PDFThe aim of this study was to investigate the efficacy of navel orange, Citrus sinensis (L.) Osbeck, peel essential oil (NOPEO) for inhibiting spoilage fungi in potato slices. Sixteen different components accounting for 99.
View Article and Find Full Text PDFObjective: To examine the platelet recovering and anti-inflammatory effects of IL-11 in the treatment of sepsis, accompanied with thrombocytopenia and to investigate the associated mechanisms via a case-control study.
Methods: 105 patients enrolled for the study were segregated into (1) IL-11 therapy group and (2) conventional therapy group. The IL-11 therapy group was given additional recombinant human IL-11 treatment.
Objective: To investigate the chemical constituents of root of Rubus biflorus.
Methods: Isolation and purification were carried out by silica gel column chromatography and recrystallization and so on. Structural determination of the pure compounds was based on physico-chemical properties and various spectral data analysis (1H-NMR, 13C-NMR, IR, EI-MS).